مقایسه اثر هشت هفته تمرین در آب، نردبان مقاومتی و دویدن استقامتی بر کاتالاز، مالون دی آلدئید، واسپین و مقاومت به انسولین در موش‌های بزرگ آزمایشگاهی نر

نوع مقاله : مقاله پژوهشی

نویسندگان

گروه فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه تربیت دبیر شهید رجائی، تهران ایران

چکیده

مقدمه و هدف: افزایش پراکسیداسیون لیپیدی و بر هم خوردن تعادل ادیپوکاین های موثر در حساسیت انسولین مانند واسپین می توانند در بروز آترواسکلروزیس و پیشرفت آن موثر باشند. هدف از تحقیق حاضر مقایسه و تعیین تاثیر هشت هفته تمرین در آب، نردبان مقاومتی و دویدن استقامتی بر کاتالاز (CAT)، مالون دی آلدئید (MDA)، واسپین و مقاومت به انسولین در موش های بزرگ آزمایشگاهی نر بود .
مواد و روش ها: 41 سر موش بزرگ آزمایشگاهی نر بطور تصادفی در 5 گروه (تمرین در آب، نردبان مقاومتی، دویدن استقامتی، شم و کنترل) تقسیم شدند . بعد از دو هفته سازگاری با محیط و یادگیری تمرین، گروه های تمرینی برای هشت هفته به تمرین ورزشی پرداختند. از روش الایزا و مدل هموستاز مقاومت به انسولین برای اندازه گیری شاخص های تحقیق استفاده شد.
نتایج: هشت هفته تمرین مقاومتی به طور معنی داری بیشتر از دو روش تمرینی دیگر باعث افزایش فعالیت آنزیم کاتالاز و کاهش MDA سِرم شد. بیشتر اینکه هشت هفته تمرین دویدن استقامتی و تمرین در آب به طور معنی دار و بیشتری  باعث کاهش واسپین سِرم و مقاومت به انسولین نسبت به تمرین مقاومتی شد (p<0.05).  
نتیجه گیری: به نظر می رسد که تمرین مقاومتی نسبت به دو روش تمرینی دیگر در کاهش پراکسیداسیون لیپیدی به لحاظ اثر برتر است، در حالی که  تمرین دویدن استقامتی و تمرین در آب نسبت به تمرین مقاومتی باعث کاهش بیشتری در  واسپین و مقاومت به انسولین می شوند.

کلیدواژه‌ها

عنوان مقاله [English]

Comparison of the effect of eight-week training in water, resistance ladder and endurance running on catalase, malondialdehyde, vaspin and insulin resistance in male rats

نویسندگان [English]

  • Mojtaba Sadegh Ghomi
  • Majid Kashef
  • Fereshteh Shahidi
  • Mojtaba Salehpour
  • Mehri Javadieh
  • Mohammad Javad Noroozi Nia
Department of Exercise Physiology, Faculty of Sport Science, Shahid Rajaee Teacher training University, Tehran, Iran
چکیده [English]

Background and Objective: Increased lipid peroxidation and imbalance of adipokines that affect insulin sensitivity such as vaspin can be effective in the development and progression of atherosclerosis. The aim of present study was comparison and determination of effect of eight-week training in water, resistance ladder and endurance running on catalase (CAT), malondialdehyde (MDA), vaspin and insulin resistance in male rats.
Materials and Methods: A total of 41 male rats were randomly divided into 5 groups (training in water, resistance ladder, endurance running, sham and control). After two weeks of adapting to the environment and learning the exercises, the training groups exercised for eight weeks. To measure study indices, we used ELISA method and the formula of insulin resistance homeostasis model. One-way analysis of variance and Tukey's post hoc test were used to test the hypotheses.
Results: Eight-week of resistance training significantly increased catalase activity and decreased serum MDA levels more than the other two training methods. Moreover, eight weeks of endurance running and water training significantly reduced serum VASPIN and insulin resistance compared to resistance training (p<0.05).
Conclusion: It seems that resistance training to be superior to the other two training methods in reducing lipid peroxidation, while endurance running and training in water result in greater reductions in VASPIN and insulin resistance than resistance training.

کلیدواژه‌ها [English]

  • Training
  • Catalase
  • Malondialdehyde
  • Vaspin
  • Rat

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دانشور پزشکی
دوره 29، شماره 6 - شماره پیاپی 157
بهمن و اسفند 1400
صفحه 58-69

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