ارتباط سابقه کولیک شیرخواری با میگرن در کودکان مراجعه‌کننده به درمانگاه‌های اعصاب کودکان ارومیه در سال 1402 Correlation Between History of Infant Colic and Migraine in Children Referred to Children's Neurology Clinics in Urmia in 1402

نوع مقاله : مقاله پژوهشی

نویسندگان

1 1دانشیار گروه بیماری‌های کودکان، دانشکده پزشکی، دانشگاه علوم پزشکی ارومیه، ارومیه، ایران

2 استادیار گروه بیماری‌های کودکان، دانشکده پزشکی، دانشگاه علوم پزشکی ارومیه، ارومیه، ایران

3 دانشجوی پزشکی عمومی، دانشکده پزشکی، دانشگاه علوم پزشکی ارومیه، ارومیه، ایران

چکیده

زمینه ‌و هدف: کولیک شیرخوارگی یک مشکل شایع در سه‌ ماهه ابتدایی زندگی نوزادان می‌باشد. میگرن از علل شایع سردردهای اولیه در دوران کودکی است. پاتوژنز کولیک شیرخوارگی و میگرن ناشناخته است. با این‌حال، شواهدی مبنی‌بر ارتباط سردردهای میگرنی در کودکی و نوجوانی با کولیک شیرخوارگی وجود دارد. مطالعه حاضر با هدف تعیین ارتباط سابقه کولیک شیرخوارگی با میگرن در کودکان مراجعه‌کننده به درمانگاه‌های اعصاب کودکان ارومیه انجام شد.
مواد و روش‌ها: این مطالعه به‌روش مورد-شاهدی روی 200 کودک 6-18 ساله مراجعه‌کننده به درمانگاه‌های اعصاب کودکان ارومیه (سال 1402) در دو گروه مبتلا به سردردهای میگرنی (100 نفر، گروه مورد) و غیرمبتلا به سردردهای میگرنی (100 نفر، گروه شاهد) انجام شد. اطلاعات لازم با پرسش از والدین و شواهد پزشکی جمع‌آوری و تجزیه‌و‌تحلیل داده‌ها با استفاده از آزمون‌های t مستقل و مجذور کای انجام شد.
نتایج: میانگین سنی کودکان مبتلا به میگرن 2/3±3/11 سال و در گروه شاهد  1/2±6/10 بود، که به ترتیب 52 درصد و 42 درصد از آن‌ها پسر بودند. از نظر سن و جنسیت تفاوت معنی‌داری بین گروه‌های مورد و شاهد مشاهده نشد (به‌ترتیب 277/0P= و 202/0P=). نتایج نشان‌دهنده ارتباط معنی‌دار کولیک شیرخوارگی (001/0P<)، سابقه خانوادگی میگرن (001/0P<) و کولیک شیرخوارگی در فرزند دیگر خانواده (001/0P<) با احتمال بروز سردردهای میگرنی در آینده بود.
نتیجه‌گیری: این مطالعه شواهدی مبنی‌بر وجود ارتباط کولیک نوازادی، سابقه خانوادگی میگرن و کولیک شیرخوارگی در فرزند دیگر خانواده با احتمال بروز سردردهای میگرنی در دوران کودکی و نوجوانی ارائه می‌دهد. با این‌حال، باتوجه‌ به محدودیت‌های مطالعه از جمله گذشته‌نگر بودن و احتمال سوگیری یادآوری، نتایج این مطالعه باید با مطالعات آتی تکمیل شود.
Background and Objective: Infantile colic is a prevalent condition during the first three months of an infant's life. Migraine is a frequent cause of recurrent primary headache in childhood. The pathogenesis of infantile colic and migraine remains unclear. However, evidence suggests an association between childhood and adolescent migraine headaches and infantile colic. This study aimed to investigate the association between a history of infantile colic and migraine in children referred to the Urmia Pediatric Neurology Clinics.
Materials and Methods: This case-control study was conducted on 200 children aged 6–18 years who were referred to Urmia Pediatric Neurology Clinics in 1402. Participants were divided into two groups: those with migraine headaches (n=100) and those without (n=100), serving as the case and control groups, respectively. Data were collected through parental interviews and medical records. Statistical analyses were performed using independent t-tests and Fisher's exact test.
Results: The mean age of the children with migraine was 11.3±3.2 years and in control group was 10.6±2.1, with 52% and 42% being male in case and control group, respectively. No significant differences in age or sex were observed between the case and control groups (P=0.277 and P=0.202, respectively). The results indicated a significant association between infantile colic (P<0.001), family history of migraine (P<0.001), and the presence of infantile colic in another child in the family (P<0.001) with the likelihood of developing migraine headaches in the future.
Conclusion: This study provides evidence that infantile colic, a family history of migraine, and the occurrence of infantile colic in another child in the family are associated with an increased likelihood of developing migraine headaches in childhood and adolescence. However, owing to the study's limitations, including its retrospective nature and potential recall bias, further research is necessary to corroborate these findings.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

Correlation Between History of Infant Colic and Migraine in Children Referred to Children's Neurology Clinics in Urmia in 1402

نویسندگان [English]

  • Ezatollah Abbasi 1
  • Alireza Abdi 2
  • Shima Abbasi 3
1 Department of pediatric diseases, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran
2 Department of pediatrics disease, School of medicine, Urmia University of medical science, Urmia, Iran
3 Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran
چکیده [English]

Background and Objective: Infantile colic is a prevalent condition during the first three months of an infant's life. Migraine is a frequent cause of recurrent primary headache in childhood. The pathogenesis of infantile colic and migraine remains unclear. However, evidence suggests an association between childhood and adolescent migraine headaches and infantile colic. This study aimed to investigate the association between a history of infantile colic and migraine in children referred to the Urmia Pediatric Neurology Clinics.
Materials and Methods: This cross-sectional analytical study was conducted on 200 children aged 6–18 years who were referred to Urmia Pediatric Neurology Clinics in 1402. Participants were divided into two groups: those with migraine headaches (n=100) and those without (n=100), serving as the case and control groups, respectively. Data were collected through parental interviews and medical records. Statistical analyses were performed using independent t-tests and Fisher's exact test.
Results: The mean age of the children with migraine was 11.3±3.2 years, with 52% being male. No significant differences in age or sex were observed between the case and control groups (P=0.277 and P=0.202, respectively). The results indicated a significant association between infantile colic (P<0.001), family history of migraine (P<0.001), and the presence of infantile colic in another child in the family (P<0.001) with the likelihood of developing migraine headaches in the future.
Conclusion: This study provides evidence that infantile colic, a family history of migraine, and the occurrence of infantile colic in another child in the family are associated with an increased likelihood of developing migraine headaches in childhood and adolescence. However, owing to the study's limitations, including its retrospective nature and potential recall bias, further research is necessary to corroborate these findings.

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دانشور پزشکی
دوره 33، شماره 1 - شماره پیاپی 176
فروردین و اردیبهشت 1404
صفحه 47-52

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