تأثیر یک دوره تمرین تناوبی شدید (HIIT) بر مقادیر سرمی پاراتورمون، آلکالین فسفاتاز و مواد معدنی استخوان در زنان یائسه

نوع مقاله : مقاله پژوهشی

نویسندگان

گروه فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه الزهرا (س)، تهران، ایران

چکیده

مقدمه و هدف: هدف از پژوهش حاضر تعیین تأثیر یک دوره HIIT بر مقادیر سرمی پاراتورمون، آلکالین فسفاتاز و مواد معدنی استخوان در زنان یائسه بود.
مواد و روش ها: در پژوهشی نیمه تجربی، 24 زن یائسه غیر فعال به صورت تصادفی به دو گروه 12 نفره کنترل و تمرین تقسیم شدند. گروه تمرین، HIIT را 3 جلسه در هفته به مدت 8 هفته انجام داد. 24 ساعت قبل از دوره آزمایشی و 48 بعد از آخرین جلسه تمرینی ویژگی­های آنتروپومتری آزمودنی­ها شامل قد، وزن، توده عضله اسکلتی (SMM)، توده چربی بدن (BFM)، درصد چربی بدن (BF%)، شاخص توده بدنی (BMI)، نسبت دور کمر به لگن (WHR)، و نمونه­های سرمی پاراتورمون، آلکالین فسفاتاز، فسفر و کلسیم اندازه­گیری شد. برای مقایسه میانگین دو گروه در دو زمان از آزمون تحلیل واریانس دو طرفه با اندازه­گیری مکرر استفاده شد.
نتایج: بین وزن و BMI دو گروه در دو زمان تفاوت معنی­داری وجود نداشت (05/0P>)؛ اما بین  SMM، BFM، BF% و WHR تفاوت معنی­داری وجود داشت (05/0P<)، به طوری که SMM در گروه تمرین نسبت به گروه کنترل افزایش معنی­داری و BFM، BF% و WHR کاهش معنی­داری یافت (05/0P<). همچنین، بین مقادیر سرمی پاراتورمون، آلکالین فسفاتاز، فسفر و کلسیم دو گروه در دو زمان تفاوت معنی­داری وجود داشت (05/0P<)، به طوری که این متغیرها در گروه تمرین نسبت به گروه کنترل افزایش معنی­داری یافت (05/0P<).
نتیجه‌گیری: یک دوره HIIT همراه با بهبود ویژگی­های آنتروپومتری می­تواند بر مقادیر سرمی پاراتورمون، آلکالین فسفاتاز و مواد معدنی استخوان در زنان یائسه تأثیر مثبتی داشته باشد.

کلیدواژه‌ها

موضوعات


عنوان مقاله [English]

The effect of a period of high-intensity interval training (HIIT) on serum levels of parathormone, alkaline phosphatase and bone mineral in postmenopausal women

نویسندگان [English]

  • Fahimeh Kazemi
  • Zeinab Mohammadi
Department of Exercise Physiology, Faculty of Sport Sciences, Alzahra University, Tehran, Iran
چکیده [English]

Background and Objective: The present research aimed to determine the effect of a period of high-intensity interval training (HIIT) on serum levels of parathormone, alkaline phosphatase, and bone mineral in postmenopausal women.
Materials and Methods: In a semi-experimental research, 24 sedentary postmenopausal women were randomly divided into control (n=12) and training (n=12) groups. The training group performed HIIT, 3 sessions per week for 8 weeks. 24 hours before the experimental period and 48 hours after the last training session, the subjects' anthropometric characteristics, including height, weight, skeletal muscle mass (SMM), body fat mass (BFM), body fat percent (BF%), body mass index (BMI), waist-to-hip ratio (WHR), and serum levels of parathyroid hormone, alkaline phosphatase, phosphorus, and calcium were measured. To compare the mean of two groups at two times, two-way repeated measures analysis of variance was used.
Results: There was no significant difference between the weight and BMI of the two groups at two times (P>0.05), but there was a significant difference between the SMM, BFM, BF%, and WHR (P<0.05), so SMM of the training group increased significantly compared to the control group and BFM, BF%, and WHR decreased significantly (P<0.05). Also, there was a significant difference between serum levels of parathormone, alkaline phosphatase, phosphorus, and calcium of the two groups at two times (P<0.05), so these variables in the training group increased compared to the control group (P<0.05).
Conclusion: A period of HIIT with improving anthropometric characteristics can have a positive effect on serum levels of parathormone, alkaline phosphatase, and bone mineral in postmenopausal women.

کلیدواژه‌ها [English]

  • Alkaline phosphatase
  • Calcium
  • High-intensity interval training
  • Parathormone
  • Phosphorus
  • Postmenopausal women
  1. Malandish A, Sheikhlou Z, Tartibian B, Rahmati-Yamch M. The effect of 12 weeks of aerobic exercise intervention on bone mineral density, expression of lymphocyte alkaline phosphatase gene and bone turnover markers in overweight postmenopausal women: a randomized controlled trial. Journal of Exercise & Organ Cross Talk. 2021;1(2):6676.
  2. Tolouei Azar J, Ghaffari GH, Tofighi1 A. Effect of 8 weeks of selected aquatic aerobic training on bone formation and density indices in overweight middleaged men. Medical Journal of Tabriz University of Medical Sciences. 2019;41(5):89-98. [In Persian]
  3. Abbaszadeh sorati , Farzaneg P. Detraining effects after sixteen weeks aerobic exercise on serum levels of Calcitonin and Parathyroid hormones in middle-aged women with osteopenia. Medical Journal of Mashhad University of Medical Sciences. 2018;61(3):997-1006. [In Persian]
  4. Moazzami M, Jamali FS. The effect of 6-months aerobic exercises on bone-specific alkaline phosphatase and parathyroid hormone in obese inactive woman. Journal of Sport and Biomotor Sciences. 2013-2014;10(2):71-9. [In Persian]
  5. Dehghan K, Jalali Dehkordi KH, Taghian F, Kargarfard M, Abedi B. The effect of 12 weeks of resistance circuit-based training on markers of bone mass metabolic and hormonal in elderly men. Sport Physiology. 2023;14(56):51-82. [In Persian]
  6. Tartibian B, Fasihi L, Eslami R. Correlation between serum calcium, phosphorus, and alkaline phosphatase indices with lumbar bone mineral density in active and inactive postmenopausal women. Journal of Arak University of Medical Sciences. 2022;25(1):120-33. [In Persian]
  7. Naghibi M. Response of ostosis metabolic markers to aerobic exercise with blood flow restriction and vitamin D supplement among middle aged females. Research in Sport Medicine and Technology. 2019;17(17):61-72. [In Persian]
  8. Shariati M, Azarbayjani MA, Zilaei Bouri S, Kaka G. The effect of eight weeks of aerobic exercise and vitamin-d supplementation on osteocalcine and alkaline pphosphatase in rats poisoned with H2O2. Iranian Journal of Nutrition Sciences and Food Technology. 2019;14(2):1-10. [In Persian]
  9. Mohebbi R, Shojaa M, Kohl M, von Stengel S, Jakob F, Kerschan-Schindl K, et al. Exercise training and bone mineral density in postmenopausal women: an updated systematic review and meta-analysis of intervention studies with emphasis on potential moderators. Osteoporosis International. 2023;34(7):1145-78.
  10. Mohamed ME, Keshak WA, Hosny A, Elsisi HF. Parathormone and Serum Calcium Response to Moderate Intensity Treadmill Exercise in Elderly. Egyptian Journal of physical therapy. 2021;8(1):8-14.
  11. Habibnezhad M, Askari B, Farajtabar Behrestaq S, Askari A. The effect of detraining following an endurance training program on bone metabolism markers in asthmatic men. Medical Laboratory Journal. 2023;17(4):13-6.
  12. Smith C, Tacey A, Mesinovic J, Scott D, Lin X, Brennan-Speranza TC, Lewis JR, Duque G, Levinger I. The effects of acute exercise on bone turnover markers in middle-aged and older adults: A systematic review. Bone. 2021;143:115766.
  13. Kitagawa T, Hiraya K, Denda T, Yamamoto S. A comparison of different exercise intensities for improving bone mineral density in postmenopausal women with osteoporosis: A systematic review and meta-analysis. Bone Reports. 2022;17:101631.
  14. Wen HJ, Huang TH, Li TL, Chong PN, Ang BS. Effects of short-term step aerobics exercise on bone metabolism and functional fitness in postmenopausal women with low bone mass. Osteoporosis International. 2017;28(2):539-47.
  15. Sen EI, Esmaeilzadeh S, Eskiyurt N. Effects of whole-body vibration and high impact exercises on the bone metabolism and functional mobility in postmenopausal women. Journal of Bone and Mineral Metabolism. 2020;38(3):392-404.
  16. Manaye S, Cheran K, Murthy C, Bornemann EA, Kamma HK, Alabbas M, et al. The Role of High-intensity and High-impact Exercises in Improving Bone Health in Postmenopausal Women: A Systematic Review. Cureus. 2023;15(2):e34644.
  17. Buckinx F, Aubertin-Leheudre M. Menopause and high-intensity interval training: effects on body composition and physical performance. Menopause. 2019;26(11):1232-3.
  18. Nunes PRP, Martins FM, Souza AP, Carneiro MAS, Nomelini RS, Michelin MA, et al. Comparative effects of high-intensity interval training with combined training on physical function markers in obese postmenopausal women: a randomized controlled trial. Menopause. 2019;26(11):1242-9.
  19. Hettchen M, von Stengel S, Kohl M, Murphy MH, Shojaa M, Ghasemikaram M, et al. Changes in menopausal risk factors in early postmenopausal osteopenic women after 13 months of high-intensity exercise: the randomized controlled ACTLIFE-RCT. Clinical Interventions in Aging. 2021;16:83-96.
  20. Aboarrage Junior AM, Teixeira CVS, Dos Santos RN, Machado AF, Evangelista AL, Rica RL, et al. A High-Intensity Jump-Based Aquatic Exercise Program Improves Bone Mineral Density and Functional Fitness in Postmenopausal Women. Rejuvenation Research. 2018;21(6):535-40.
  21. Kim JS, Jeon J, An JJ, Yi HK. Interval running training improves age-related skeletal muscle wasting and bone loss: Experiments with ovariectomized rats. Experimental Physiology. 2019;104(5):691-703.
  22. Rabiee MR, Daryanoosh F, Salesi M, Tahmasebi R, Koushkie Jahromi M. The effect of eight weeks of mediterranean diet and high-intensity interval training on body composition in obese and overweight premenopausal women. International Journal of Nutrition Sciences. 2023;8(2):117-24.
  23. Dupuit M, Maillard F, Pereira B, Marquezi ML, Lancha AH Jr, Boisseau N. Effect of high intensity interval training on body composition in women before and after menopause: a meta-analysis. Experimental Physiology. 2020;105(9):1470-90.
  24. Maillard F, Pereira, B, Boisseau N. Effect of high-intensity interval training on total, abdominal and visceral fat mass: A meta-analysis. Sports Medicine. 2018;48(2):269-88.
  25. Hashimoto, H., Shikuma, S., Mandai, S. et al. Calcium-based phosphate binder use is associated with lower risk of osteoporosis in hemodialysis patients. Scientific Reports. 2021;11(1):1648.
  26. Troy KL, Mancuso ME, Butler TA, Johnson JE. Exercise Early and Often: Effects of Physical Activity and Exercise on Women's Bone Health. International Journal of Environmental Research and Public Health. 2018;28:15(5):878.