علل ایجاد حمله آسم در کودکان مراجعه کننده به اورژانس بیمارستان طالقانی گرگان در سال 1401

نوع مقاله : مقاله پژوهشی

نویسندگان

مرکز تحقیقات سلامت کودکان و نوزادان، دانشگاه علوم پزشکی گلستان، گرگان، ایران

چکیده

مقدمه و هدف: عدم کنترل بیماری آسم در کودکان می تواند منجر به تشدید بیماری و ایجاد بحران های حیاتی برای کودکان گردد. مطالعه حاضر به بررسی شیوع آسم و محرک های محیطی مرتبط با حملات آسمی در کودکان پرداخته است.
مواد و روش ها: در این مطالعه مقطعی، کودکان مبتلا به آسم مراجعه کننده به اورژانس در سال 1401 مورد بررسی قرار گرفتند. اطلاعات حاصل از معاینه بالینی، ویژگی های دموگرافیک و مواجهه با محرک های مختلف بیماری، تعداد دفعات بستری و حملات آسمی و شدت بیماری از طریق چک لیست محقق ساخته جمع آوری شد. جهت مقایسه داده ها از آزمون کای دو استفاده گردید.
نتایج: 47 بیمار با میانگین سنی 6/3 ± 53/4 سال و شامل 14 (30 %) دختر و 33 (70 %) پسر مورد بررسی قرار گرفتند. 51 % بیماران آسم متوسط داشتند. فراوانی بیماران با یک نوبت بستری (8/63 %) و بیماران با یک نوبت حمله آسمی (7/61 %) به طور معنی داری بیشتر از سایر تعداد دفعات بستری و حملات آسمی بود (05/0>P). عفونت های تنفسی و آلرژن های محیطی فراوان ترین محرک های آسم بودند (به ترتیب 5/74 % و 6/42 %). فراوانی بیماران بر اساس محل سکونت و مصرف آنتی بیوتیک تفاوت معنی داری نشان نداد (05/0<P).
نتیجه‌گیری: شیوع بیشتر آسم متوسط، یک نوبت بستری و یک نوبت حمله آسمی در کودکان نشان داد که برنامه ریزی و آموزش و همچنین کنترل محرک های آسمی می تواند در پیشگیری از حملات آسمی در کودکان موثر باشد.

کلیدواژه‌ها

موضوعات


عنوان مقاله [English]

Causes of asthma attacks in children referred to the emergency ward of Taleghani hospital in Gorgan in 2022

نویسندگان [English]

  • Mohsen Ebrahimi
  • Sarvenaz Ghodsi rasi
  • Seyed Ali Aghapour
  • Azam Rashidbaghan
Neonatal and Children’s Health Research Center, Golestan University of Medical Sciences, Gorgan, Iran
چکیده [English]

Background and Objective: Failure to control asthma in children can lead to exacerbation of the disease and cause critical crises for children. The present study investigated the incidence of asthma and environmental triggers associated with asthma attacks in children.
Materials and Methods: In this cross-sectional study, children with asthma referred to agency were evaluated in 2022. The data obtained from clinical examination, demographic characteristics and exposure to various disease triggers, the number of hospitalizations and asthma attacks and the severity of the disease were collected and compared through a checklist. Chi-square test were used to compare the data. 
Results: Forty seven patients with the mean of age 4.53 ± 3.6 and including 14 (30%) girls and 33 (70%) were boys were studied. Fifty one percent of patients had moderate asthma. The frequency of patients with one episode of hospitalization (63.8%) and patients with one episode of asthma attack (61.7%) was significantly higher than the other number of hospitalizations and asthma attacks (P<0.05). Among asthma triggers, respiratory infections and environmental allergens were the most frequent (74.5% and 42.6%, respectively). Place of residence and antibiotic use did not show any significant difference in patients (P<0.05).
Conclusion: Higher prevalence of moderate asthma, one hospitalization and one asthma attack in children showed that planning and education as well as control of asthma triggers can be effective in preventing asthma attacks in children.

کلیدواژه‌ها [English]

  • Pediatric asthma attack
  • Respiratory system infections
  • Allergens
  1. Pardue Jones B, Fleming GM, Otillio JK, Asokan I, Arnold DH. Pediatric acute asthma exacerbations: Evaluation and management from emergency department to intensive care unit. Journal of Asthma 2016;53(6):607-17.
  2. Moorman JE, Akinbami LJ, Bailey CM, Zahran HS, King ME, Johnson CA, et al. National surveillance of asthma: United States, 2001-2010. Vital & health statistics Series 3, Analytical and epidemiological studies 2012(35):1-58.
  3. Miller AG, Breslin ME, Pineda LC, Fox JW. An asthma protocol improved adherence to evidence-based guidelines for pediatric subjects with status asthmaticus in the emergency department. Respiratory care 2015;60(12):1759-64.
  4. Restrepo RD, Peters J. Near-fatal asthma: recognition and management. Current opinion in pulmonary medicine 2008;14(1):13-23.
  5. Cohen HA, Blau H, Hoshen M, Batat E, Balicer RD. Seasonality of asthma: a retrospective population study. Pediatrics 2014;133(4):e923-e32.
  6. Dondi A, Calamelli E, Piccinno V, Ricci G, Corsini I, Biagi C, et al. Acute asthma in the pediatric emergency department: infections are the main triggers of exacerbations. BioMed research international 2017;2017.
  7. Fuhlbrigge A, Peden D, Apter AJ, Boushey HA, Camargo Jr CA, Gern J, et al. Asthma outcomes: exacerbations. Journal of Allergy and Clinical Immunology 2012;129(3): S34-S48.
  8. Bacharier L, Boner A, Carlsen KH, Eigenmann P, Frischer T, Götz M, et al. Diagnosis and treatment of asthma in childhood: a PRACTALL consensus report. Allergy 2008;63(1):5-34.
  9. Beasley R, Crane J, Lai CK, Pearce N. Prevalence and etiology of asthma. Journal of allergy and clinical immunology 2000;105(2):S466-S72.
  10. Haselkorn T, Fish JE, Zeiger RS, Szefler SJ, Miller DP, Chipps BE, et al. Consistently very poorly controlled asthma, as defined by the impairment domain of the Expert Panel Report 3 guidelines, increases risk for future severe asthma exacerbations in The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study. Journal of allergy and clinical immunology 2009;124(5):895-902. e4.
  11. Moore WC, Bleecker ER, Curran-Everett D, Erzurum SC, Ameredes BT, Bacharier L, et al. Characterization of the severe asthma phenotype by the national heart, lung, and blood institute's severe asthma research program. Journal of Allergy and Clinical Immunology 2007;119(2):405-13.
  12. Rust G, Zhang S, Reynolds J. Inhaled corticosteroid adherence and emergency department utilization among Medicaid-enrolled children with asthma. Journal of Asthma 2013;50(7):769-75.
  13. Chipps BE, Zeiger RS, Borish L, Wenzel SE, Yegin A, Hayden ML, et al. Key findings and clinical implications from The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study. Journal of Allergy and Clinical Immunology 2012;130(2):332-42. e10.
  14. Johnston NW, Johnston SL, Duncan JM, Greene JM, Kebadze T, Keith PK, et al. The September epidemic of asthma exacerbations in children: a search for etiology. Journal of Allergy and Clinical Immunology 2005;115(1):132-8.
  15. Murray CS, Poletti G, Kebadze T, Morris J, Woodcock A, Johnston S, et al. Study of modifiable risk factors for asthma exacerbations: virus infection and allergen exposure increase the risk of asthma hospital admissions in children. Thorax 2006;61(5):376-82.
  16. Assessment CEPAOoEHH. Health effects of exposure to environmental tobacco smoke: The Office; 1997.
  17. Chauhan A, Inskip HM, Linaker CH, Smith S, Schreiber J, Johnston SL, et al. Personal exposure to nitrogen dioxide (NO2) and the severity of virus-induced asthma in children. The Lancet 2003;361(9373):1939-44.
  18. Bisgaard H, Bønnelykke K, Sleiman PM, Brasholt M, Chawes B, Kreiner-Møller E, et al. Chromosome 17q21 gene variants are associated with asthma and exacerbations but not atopy in early childhood. American journal of respiratory and critical care medicine 2009;179(3):179-85.
  19. Belessis Y, Dixon S, Thomsen A, Duffy B, Rawlinson W, Henry R, et al. Risk factors for an intensive care unit admission in children with asthma. Pediatric pulmonology 2004;37(3):201-9.
  20. Ryan KS, Son S, Roddy M, Siraj S, McKinley SD, Nakagawa TA, et al. Pediatric asthma severity scores distinguish suitable inpatient level of care for children admitted for status asthmaticus. Journal of Asthma 2021;58(2):151-9.
  21. Kazi U, Rukh SG, Zawawi S, Laila S, Fareeduddin M, Saleem SG. To determine the association between asthma severity and hospital admission measured by Pediatric Respiratory Assessment Measure (PRAM) score at Indus Hospital and Health Network, Karachi, Pakistan, 2020-2021. Pakistan Journal of Medical Sciences 2022;38(2):345.
  22. Carroll WD, Lenney W, Child F, Strange RC, Jones PW, Whyte MK, et al. Asthma severity and atopy: how clear is the relationship? Archives of disease in childhood 2006;91(5):405-9.
  23. Khetsuriani N, Kazerouni NN, Erdman DD, Lu X, Redd SC, Anderson LJ, et al. Prevalence of viral respiratory tract infections in children with asthma. Journal of Allergy and Clinical Immunology. 2007;119(2):314-21
  24. Gabet S, Rancière F, Just J, de Blic J, Lezmi G, Amat F, et al. Asthma and allergic rhinitis risk depends on house dust mite specific IgE levels in PARIS birth cohort children. World Allergy Organization Journal 2019;12(9):100057.
  25. Martinez F. Role of respiratory infection in onset of asthma and chronic obstructive pulmonary disease. Clinical & Experimental Allergy 1999;29:53-8.
  26. Panitch HB. Evaluation of recurrent pneumonia. The Pediatric infectious disease journal 2005;24(3):265-6