پاسخ سطوح پلاسمایی آیریزین، فولیستاتین و FGF21 به تمرینات هوازی در زنان بهبودیافته از کووید-19

نوع مقاله : مقاله پژوهشی

نویسندگان

1 گروه تربیت بدنی و علوم ورزشی، واحد علوم و تحقیقات، دانشگاه آزاد اسلامی، تهران، ایران

2 گروه بیماری‌های عفونی، دانشگاه علوم پزشکی، آبادان، ایران

3 گروه فیزیولوژی، دانشگاه علوم پزشکی، آبادان، ایران

چکیده

مقدمه و هدف: به‌تازگی انجام فعالیت‌های ورزشی منظم به‌واسطه ترشح مایوکاین‌ها به‌عنوان راهکاری مناسب جهت بازتوانی، کنترل عوارض و پیامدهای مرتبط با کووید-19 مورد توجه قرار گرفته است. هدف از انجام این مطالعه بررسی پاسخ سطوح پلاسمایی آیریزین، فولیستاتین و فاکتور رشد فیبروبلاست 21 (FGF21) به تمرینات هوازی در زنان بهبودیافته از کووید-19 بود.
مواد و روش ها: 22 زن بهبودیافته از کووید-19 شهرستان‌های آبادان و خرمشهر پس از فراخوان عمومی و گزینش در دو گروه 11 نفره شامل گروه تمرین هوازی و گروه کنترل تقسیم‌بندی شدند. گروه تمرینات هوازی پروتکل تمرینی را با شدت 50 تا 70 درصد ضربان قلب ذخیره و به مدت هشت هفته (سه جلسه در هفته) اجرا کردند. قبل و پس از پایان پروتکل تمرینی نمونه‌های خونی جمع‌آوری شد و اندازه‌گیری سطوح آیریزین، فولیستاتین و FGF21 به روش الایزا انجام شد. داده‌ها با استفاده از آزمون آماری کوواریانس (آنکوا) در سطح (05/0>P) آنالیز شد.
نتایج: بر اساس مقایسه بین‌گروهی داده‌ها، مقادیر آیریزین (05/0>P)، فولیستاتین (05/0>P) و FGF21 و(05/0>P) گروه هوازی در مقایسه با گروه کنترل افزایش معناداری داشته است. همچنین تغییرات درون‌گروهی آیریزین (05/0>P)، فولیستاتین (05/0>P) و FGF21) (05/0>P) نیز نشان داد که بین میانگین قبل و بعد گروه هوازی افزایش معنادار وجود دارد.
نتیجه‌گیری: انجام تمرینات هوازی در زنان بهبودیافته از کووید-19 می‌تواند در بازیابی پروفایل مایوکاینی آنها مؤثر باشد.

کلیدواژه‌ها

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دانشور پزشکی
دوره 31، شماره 3 - شماره پیاپی 166
مرداد و شهریور 1402
صفحه 55-67

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