تاثیر هشت هفته تمرین مقاومتی اینتروال با شدت زیاد بر سطوح سیرتوئین 1 و 25-‌هیدروکسی ویتامین D در زنان دارای اضافه وزن با کمبود ویتامین D

نوع مقاله : مقاله پژوهشی

نویسندگان

1 گروه تربیت بدنی، واحد ساری، دانشگاه آزاد اسلامی، ساری، ایران

2 گروه تربیت بدنی، واحد قائمشهر، دانشگاه آزاد اسلامی، قائمشهر، ایران

چکیده

مقدمه و هدف: شیوع اضافه وزنی و کم تحرکی از مشکلات مهم بهداشتی در جهان محسوب می شود که با بروز استرس اکسایشی و کمبود ویتامین D همراه می‌باشند. در مطالعه حاضر تاثیر هشت هفته تمرین مقاومتی اینتروال با شدت زیاد (High-intensity Interval Resistance Training: HIIRT) برسطوح سیرتوئین 1 و 25- هیدروکسی ویتامین D در زنان دارای اضافه وزن با کمبود ویتامین D بررسی شد.
مواد و روش ها: مطالعه حاضر  به صورت نیمه تجربی بر روی 26 زن جوان غیر فعال دارای اضافه وزن، با کمبود ویتامین D انجام شد. آزمودنی‌ها به صورت دسترس و هدفمند انتخاب و سپس به طور تصادفی در گروه های مداخله و کنترل قرار گرفتند. تمرین اصلی شامل سه ست با 150 ثانیه استراحت بین ست ها بود. هر ست با 6 تکرار در شدت 80 % یک تکرار بیشینه شروع و با استراحت 20 ثانیه ای دیگر، تا رسیدن به واماندگی ادامه می یافت (2 یا 3 تکرار بعدی).  داده ها با استفاده از آزمون های t مستقل و تحلیل کوواریانس تک متغیره (آنکوا) در سطح معناداری 05/0≥P تجزیه و تحلیل شدند.
نتایج: مداخله HIIRT منجر به افزایش معنادار سطوح سیرتوئین 1، 25- هیدروکسی ویتامین D و هم چنین فعالیت سوپراکسید دیسموتاز در زنان داری اضافه وزن با کمبود ویتامین D شد.
نتیجه‌گیری: براساس نتایج پژوهش، HIIRT می تواند به عنوان یک مداخله غیر دارویی بخشی از اثرات حمایتی خود را در شرایط اضافه وزنی همراه کمبود ویتامین D،  بواسطه بهبود وضعیت ویتامین D و  افزایش دفاع آنتی اکسیدانی از مسیر سیرتوئین 1/ سوپراکسید دیسموتاز اعمال کند.

کلیدواژه‌ها

عنوان مقاله [English]

The effect of eight weeks of high-intensity interval resistance training on serotonin 1 and 25-hydroxyvitamin D levels in overweight women with vitamin D deficiency

نویسندگان [English]

  • Rouhollah Akbari 1
  • Abdolreza Jafari Chashmy 1
  • Masoumeh Habibian 2
1 Department of Physical Education and Sports Sciences, Sari Branch, Islamic Azad University, Sari, Iran
2 Department of Physical Education and Sports Sciences, Qaemshahar Branch, Islamic Azad University, Qaemshahar, Iran
چکیده [English]

Background and Objective: The prevalence of overweight and sedentary lifestyle is one of the major health problems in the world that are associated with oxidative stress and vitamin D deficiency. In the present study, the effect of eight weeks of high intensity interval resistance training (HIIRT) on Sirtuin 1 and 25-hydroxyvitamin D levels in overweight women with vitamin D deficiency was investigated.
Materials and Methods: This is a quasi-experimental study that was carried out on 26 overweight young inactive women with vitamin D deficiency. Subjects were selected accessibly and purposefully and then randomly assigned to the intervention and control groups (13 in each group). The main exercise consisted of three sets with 2.5 minutes rest between sets. Each set started with 6 repetitions at an intensity of 80% one repetition maximum and continued with another 20 seconds rest until exhaustion (2 or 3 subsequent repetitions). Data were analyzed by independent t-test and one-way analysis of covariance (ANCOVA) at the significant level of p<0.05.
Results: HIIRT intervention led to a significant increase in Sirtuin 1, 25-hydroxyvitamin D levels as well as superoxide dismutase activity in overweight women with vitamin D deficiency.
Conclusion: According to the results of the study, HIIRT as a non-pharmacological intervention can exert some of its supportive effects in overweight conditions with vitamin D deficiency, by improving the status of vitamin D and enhancing antioxidant defense from the Sirtuin 1/ superoxide dismutase pathway.

کلیدواژه‌ها [English]

  • Overweight
  • Vitamin D
  • Sirtuin 1
  • Superoxide dismutase

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دانشور پزشکی
دوره 30، شماره 4 - شماره پیاپی 161
مهر و آبان 1401
صفحه 74-83

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