اثر فعالیت استقامتی حاد متعاقب مصرف سه دوز مختلف مکمل سیر بر فاکتور هشت، فیبرینوژن انعقادی و فشار خون سیستولی و دیاستولی در مردان جوان ورزشکار

نوع مقاله : مقاله پژوهشی

نویسندگان

1 گروه تربیت بدنی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه تبریز، تبریز، ایران

2 گروه تربیت بدنی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه محقق اردبیلی، اردبیل، ایران

چکیده

مقدمه و هدف: اثر فعالیت استقامتی حاد متعاقب دوزهای‌ سیر بر فاکتورهای انعقادی و فشار خون مشخص نیست. هدف بررسی تأثیر فعالیت استقامتی حاد متعاقب مصرف سه دوز‌ سیر بر فاکتور هشت، فیبرینوژن و فشار خون سیستولی و دیاستولی مردان ورزشکار بود.
مواد و روش ها: 15 مرد استقامتی کار (سن 88/7±27 سال، وزن 45/6±9/73 کیلوگرم، قد 33/4±35/175 سانتی متر)، داوطلبانه در تحقیق شرکت کردند. آزمودنی‌ها 4 جلسه، دوز‌های سیر (500،750 و 1000 میلی گرم) و دارونما را مصرف کرده و 4 ساعت بعد فعالیت استقامتی 30 دقیقه‌ای با شدت 85-65 درصد ضربان قلب هدف را بر روی نوار گردان انجام دادند. نمونه خونی، قبل و 4 ساعت بعد از مکمل، دارونما و فعالیت استقامتی حاد، گرفته شد. تفاوت بین دوزهای سیر متعاقب فعالیت استقامتی، با آنالیز واریانس- بونفرونی و تأثیر هر یک از دوزهای سیر و دارونما با تی-وابسته تحلیل شد
نتایج: یک جلسه فعالیت حاد استقامتی متعاقب هر سه دوز سیر، فاکتور VIII، فیبرینوژن و فشارخون سیستولی را به طور معنی داری افزایش داد (05/0˂P). این افزایش فاکتور VIII و فیبرینوژن متعاقب یک جلسه فعالیت استقامتی شدید پس از 500 میلی گرم در مقایسه با 1000 میلی گرم، به طور معنی داری کمتر بود (05/0˂P)، در حالیکه این افزایش فشار سیستولی پس از دوز 1000 میلی-گرم در مقایسه با 500 میلی گرم، به طور معنی داری کمتر بود (05/0˂P). فشار دیاستولی پس از تمرین و سیر تغییر معنی داری نداشت (05/0<P).
نتیجه‌گیری: دوز 500 میلی گرم بهترین دوز کاهنده فاکتور VIII و فیبرینوژن می باشد. در حالیکه، سیر 1000 میلی گرم در مقایسه با 500 میلی گرم بهترین دوز کاهنده فشار خون سیستولی متعاقب یک جلسه فعالیت استقامتی حاد می باشد.

کلیدواژه‌ها

عنوان مقاله [English]

The effect of acute endurance exercise after three different doses of garlic supplementation on coagulating factor VIII, fibrinogen and systolic and diastolic blood pressure in young athletic men

نویسندگان [English]

  • Roghayeh Hemmati 1
  • Saeed Dabbagh Nikukheslat 1
  • Ameneh Pourrahim Ghouroghchi 2
1 Department of Sport Physiology, Faculty of Physical Education and Sport Sciences, University of Tabriz, Tabriz, Iran
2 Department of Sport physiology, Faculty of Educational Sciences and Psychology, University of Mohaghegh-e-Ardabili, Ardabil, Iran
چکیده [English]

Background and Objective: The effect of acute endurance exercise after different garlic doses on coagulation factors and blood pressure are not clear. The aim of this study was  to assess the effect of an acute endurance exercise after three garlic doses and acute endurance exercise on factor VIII, fibrinogen and systolic and diastolic pressure in young athletic men.
Materials and Methods: Fifteen runners (age 27.0±7.9 years; weight 73.9±6.4kg, height 175.3±4.3 cm) voluntarily participated in this study. Subjects took garlic doses (500, 750 and 1000 mg) and placebo in separate sessions. In each session, 4 hour after the supplement or placebo, subjects performed 30 min running on treadmill, 65-85% target heart rate. Blood samples were taken before supplementation, before and immediately after exercise. The difference between doses of garlic after acute endurance exercise were analyzed with ANOVA-repeated measure and Bonferroni. The difference between garlic doses and placebo were analyzed with dependent t-test.
Results: An acute endurance exercise after three dosages significantly increased FVIII, fibrinogen and systolic blood pressure (P˂0.05). The increase of FVIII and Fibrinogen after 500 mg compared to 1000 mg of garlic and an acute endurance exercise was significantly more decreased (P˂0.05). However, an acute endurance training with 1000 mg compared to 500 mg of garlic significantly lower increased systolic blood pressure (P˂0.05). There were no significant difference in diastolic blood pressure after acute endurance exercise and garlic (P>0.05).
Conclusion: Dose of 500 mg compared to 1000 mg of garlic after an acute endurance exercise is the most effective dose for reducing FVIII and fibrinogen. After an acute endurance exercise, 1000 mg compared to 500 mg of garlic is the most effective dose for reducing systolic blood pressure.

کلیدواژه‌ها [English]

  • Garlic
  • Acute endurance exercise
  • Factor VIII
  • Fibrinogen
  • Systolic and diastolic pressure

مراجع

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