اثر تعاملی تمرین هوازی و مصرف مکمل جنسینگ بر فاکتور نوروتروفیک مشتق از مغز دختران 15 تا 18 سال

نویسندگان

گروه علوم ورزشی، دانشگاه سیستان و بلوچستان، زاهدان، ایران

چکیده

مقدمه و هدف: نوروتروفین­ها خانواده‌ای از عوامل رشد هستند که اساساً به واسطه توانایی‌شان در حفاظت بقای عصبی شناسایی می­شوند. خانواده نوروتروفین­ها متشکل از 4 پروتئین است که یکی از آنها، فاکتور نوروتروفیک مشتق از مغز است. هدف پژوهش، بررسی تأثیر 6 هفته تمرین هوازی و مصرف مکمل جنسینگ بر فاکتور نوروتروفیک مشتق از ‏مغز در دختران 15 تا 18 سال بود.
 
مواد و روش­ها: پژوهش، نیمه تجربی و با طرح پیش‌آزمون و پس‌آزمون با گروه کنترل انجام شد. جامعه آماری کلیه دختران 15 تا 18 ساله شهر زاهدان که از بین آنها 48 نفر به صورت داوطلبانه و هدفمند انتخاب و به صورت تصادفی در 4 گروه تمرین، تمرین+ مکمل، مکمل و کنترل قرار گرفتند. پروتکل تمرینی شامل 6 هفته دویدن در سالن (3 جلسه در هفته)، به مدت 25 تا 40 دقیقه و با شدت 60 تا 70 درصد از ضربان قلب ذخیره بود. آزمودنی­های گروه­های مکمل، جنسینگ را 500 میلی‌گرم در روز (250 میلی‌گرم صبح و 250 میلی‌گرم عصر) مصرف کردند. برای آنالیز داده­ها از روش آماری تحلیل واریانس دوراهه، آزمون تعقیبی بونفرنی و آزمون t همبسته استفاده و سطح معناداری  در نظر گرفته شد.
 
نتایج: سطوح فاکتور نوتروفیک مشتق از مغز (BDNF) به طور معناداری بعد از 6 هفته تمرین هوازی و مصرف مکمل جنسینگ در گروه تمرین+ مکمل نسبت به سایر گروه­ها افزایش یافت. بهبود مقادیر پایه شاخص‌های BDNF در گروه­های تمرین، مکمل+ تمرین و مکمل حاصل شد (05/0>P < /span>) در حالی که تغییری در شاخص­ مذکور در گروه کنترل مشاهده نشد (05/0<P < /span>).
 
نتیجه­ گیری: به نظر می‌رسد انجام تمرینات هوازی و مصرف مکمل جنسینگ اثر قابل‌توجهی بر بهبود BDNF دارد. این افزایش در همه گروه‌های تحقیق به جز گروه کنترل مشاهده شد که نشان از تأثیر ورزش و جنسینگ به صورت مستقل از هم بر BDNF داشته است.

عنوان مقاله [English]

Interactive effect of aerobic training and ginseng supplementation on brain-derived neurotrophic factor in 15-18 years old girls

نویسندگان [English]

  • Maryam Najafi
  • Majid Vahidian Rezazadeh
  • Omid Mohammaddoust
چکیده [English]

Background and Objective: Neurotrophins are a family of growth factors that are primarily identified by their ability to protect neuronal survival. The family of neurotrophins consists of 4 proteins, one of which is the brain-derived neurotrophic factor (BDNF). The purpose of the present study was to investigate the effect of 6-week aerobic training and ginseng supplementation on BDNF in 15-18 years old girls.
 
Materials and Methods: This study was a quasi-experimental with pre-test and post-test design with a control group. The statistical population of this study was all girls aged 15-18 years in Zahedan, 46 of whom were voluntarily and purposefully selected. They were randomly divided into four groups of exercise, exercise + supplement, supplement, and control. The training protocol consisted of 6 weeks of running the gym (3 times a week) for 25 to 40 minutes, with 60-70% of the heart rate reserve. Subjects in the supplemented groups consumed Ginseng trace 500 mg daily (250 mg in the morning and 250 mg in the evening). Data were analyzed using two-way ANOVA with Bonferroni post hoc test and t-test. P<0.05 was considered as significant.
 
Results: BDNF levels were significantly increased after six weeks of aerobic exercise and ginseng supplementation in the exercise + supplement group as compared to the other groups. Also, the baseline values of BDNF indices were improved in training, supplement + training and supplement groups (P <0.05). There was no change in this index in the control group (P >0.05).
 
Conclusion: It seems that aerobic exercise and ginseng supplementation have a significant effect on BDNF improvement. This increase was observed in all study groups except the control group, which showed the effect of exercise and ginseng independently on BDNF.
 

کلیدواژه‌ها [English]

  • Aerobic exercise
  • Ginseng
  • Brain-derived neurotrophic factor
  • 15-18 years old girls
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