ارتباط بین سطوح سرمی آدیپونکتین، لپتین، تری‌گلیسیرید، کلسترول و نمایۀ تودۀ بدنی پس از 12 هفته تمرین هوازی شدت متوسط در دختران دارای اضافه‌وزن

نویسندگان

1 دانشیار فیزیولوژی ورزشی، گروه آسیب‌شناسی و حرکات اصلاحی، دانشکدۀ تربیت‌بدنی و علوم ورزشی، دانشگاه علامه طباطبایی، تهران، ایران

2 دکتری فیزیولوژی ورزشی، بخش فیزیوتراپی بیمارستان امام‌خمینی، دانشگاه علوم‌پزشکی اردبیل، اردبیل، ایران

3 دانشجوی دکتری فیزیولوژی ورزشی، گروه تربیت‌بدنی و علوم ورزشی، دانشگاه محقق اردبیلی، اردبیل، ایران

چکیده

مقدمه و هدف: چاقی در دوران کودکی خطر ابتلا به بیماری‌های قلبی‌عروقی و دیابت نوع دوم را در بزرگسالی افزایش می‌دهد. هدف تحقیق حاضر بررسی ارتباط بین سطوح سرومی آدیپونکتین، لپتین، تری‌گلیسیرید و کلسترول پس از 12 هفته تمرین هوازی با شدت متوسط در دختران دارای اضافه‌وزن می‌باشد.


مواد و روش‌ها: این تحقیق از نوع تحقیقات نیمه‌تجربی با طرح پیش‌آزمون ـ پس‌آزمون بود. نوزده دختر دارای اضافه‌وزن با میانگین سن 5/1±8/9 به‌صورت داوطلبانه و پس از اخذ رضایت‌نامه در یک برنامۀ 12‌هفته‌ای تمرینات هوازی شرکت کردند. نمونه‌های خونی در شرایط پایه و پس از 12 هفته تمرینات هوازی از ورید بازویی جمع‌آوری گردید. سطوح لپتین و آدیپونکتین سرم به روش الایزا و سطوح کلسترول و تری گلیسیرید سرم به روش آنزیمی‌کالریمتری اندازه‌گیری شد. جهت تجزیه و تحلیل داده‌ها از آزمون‌های تی جفت شده، ضریب همبستگی پیرسون و تحلیل رگرسیونی در سطح معنی‌داری 05/0>p < /span> استفاده شد.


نتایج: میانگین غلظت‌های تری‌گلیسیرید، لپتین و درصد چربی آزمودنی‌ها بعد از 12 هفته تمرینات هوازی در مقایسه با شرایط پایه کاهش و آدیپونکتین افزایش معنی‌داری داشت (۰۵/۰P≤). بین مقادیر لپتین با آدیپونکتین (۶۲۱r=، 025/۰P≤) لپتین با شاخص تودۀ بدنی (۵۷۷r=، 0۱۰/۰P≤) و بین مقادیر آدیپونکتین با کلسترول (۵۹۲r=، 0۱۲/۰P≤)، آدیپونکتین با درصد چربی (۶۱۲r=، 0۱۵/۰P≤) و آدیپونکتین با شاخص تودۀ بدنی (۷۴۱r=، 0۱۸/۰P≤) ارتباط معنی‌داری مشاهده شد.


نتیجه‌گیری: 12 هفته برنامۀ فعالیت بدنی هوازی با شدت متوسط، تغییرات برجسته‌ای در ترکیب بدن، نیمرخ لیپیدی و شاخص‌های بیوشیمیایی چاقی در دختران دارای اضافه‌وزن به‌وجود می‌آورد. 

کلیدواژه‌ها


عنوان مقاله [English]

The relationship between serum levels of adiponectin, leptin, cholesterol, triglyceride and body mass index in the overweight girls after 12-week moderate intensity aerobic exercise training

چکیده [English]

Background and Objective: The childhood obesity is associated with the development of type 2 diabetes and cardiovascular disease throughout the lifecycle. The purpose of this study was to examine the relationship between adiponectin, leptin, cholesterol and triglyceride serum levels in the overweight girls after 12 weeks moderate intensity aerobic exercise training.


Materials and Methods: This research was conducted with a semi- experimental methodology with pre-test and post-test. Nineteen overweight girls (aged 9.8±1.5 years) after getting consent volunteered for this study. Subjects performed moderate intensity aerobic exercise training for 12 weeks. Blood samples were collected after overnight fasting, before and after 12 weeks of exercise training program. Total cholesterol and triglyceride levels were assessed using an enzymatic colorimetric assay (GPO-PAP). Serum leptin and adiponectin levels were determined by enzyme linked immunosorbent assay (ELISA).  Data analysis was performed by  paired sample t-test, Pearson correlation coefficient, regression analysis and a significant level of p<0.05 was considered.


Results: Body fat percentage, circulating levels of triglyceride and leptin of participants as compared to baseline after 12 weeks of aerobic exercise decreased and adiponectin significantly increased (p<0.05). A significant correlation was observed between leptin with body mass index (r=577, p<0.01) and adiponectin (r=621, p<0.025). Also, there was a significant correlation between adiponectin with cholesterol (r=592, p<0.05), body fat percentage (r=612, p<0.05) and body mass index (r=741, p<0.05).   


Conclusion: Moderate intensity aerobic exercise training caused favorable changes in body fat percentage and obesity-related metabolic biomarkers in prepubertal overweight girls. 

کلیدواژه‌ها [English]

  • Leptin
  • Adiponectin
  • Lipids
  • Girls
  • Physical activity
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