تأثیر 10 هفته تمرین ترکیبی (هوازی ـ مقاومتی) بر سطوح مولکول چسبان عروقی و نیمرخ لیپیدی در زنان چاق و دارای اضافه‌وزن

نویسندگان

1 دانشیار گروه فیزیولوژی ورزشی، دانشکدۀ تربیت‌بدنی و علوم ورزشی، دانشگاه تهران، تهران، ایران

2 کارشناس‌ارشد فیزیولوژی ورزشی، دانشکدۀ تربیت‌بدنی و علوم ورزشی، دانشگاه آزاد، تهران، ایران

3 کارشناس‌ارشد فیزیولوژی ورزشی، دانشکدۀ تربیت‌بدنی و علوم ورزشی، دانشگاه تهران، تهران، ایران

4 کارشناس‌ارشد فیزیولوژی ورزشی، دانشکده تربیت‌بدنی و علوم ورزشی، دانشگاه الزهرا، تهران، ایران

5 دکتری تخصصی فیزیولوژی ورزشی، دانشکده تربیت‌بدنی و علوم ورزشی، دانشگاه تهران، تهران، ایران

چکیده

مقدمه و هدف: مولکول‌های چسبان نقش مهمی در پاتوژنز آتروسکلروز دارند. هدف از پژوهش حاضر، تأثیر 10 هفته تمرین ترکیبی بر سطوح مولکول‌های چسبان عروقی و نیمرخ لیپیدی در زنان چاق و دارای اضافه‌وزن بود.


مواد و روش‌ها: ١٨ زن چاق و دارای اضافه‌وزن (میانگین سنی ٧/٧±٣٣/٣٩ سال؛ میانگین وزنی ١٩/٥±٥٧/٧٦ کیلوگرم)، در تحقیق حاضر، شرکت نمودند. آزمودنی‌ها به‌طور تصادفی به دو گروه تجربی و کنترل تقسیم شدند. آزمودنی‌های گروه تجربی، تمرین ترکیبی را به‌صورت تمرین هوازی (60تا75درصد ضربان قلب بیشینه) و تمرین مقاومتی (2 دوره با 1۰تا1۲ تکرار در هر جلسه و با شدت ۴0تا۶0درصد یک تکرار بیشینه و زمان استراحت ۶۰تا۹۰ ثانیه) به‌مدت 10 هفته، هر هفته 3 جلسه انجام دادند. در طی پژوهش، گروه کنترل هیچ مداخله‌ای دریافت نکردند. در آغاز و ٤٨ ساعت پس از پایان تمرین، خونگیری به‌منظور اندازه‌گیری سطوح مولکول چسبان عروقی (VCAM-1) و لیپیدها انجام گرفت. داده‌ها با استفاده از آزمون تی مستقل در سطح ٠٥/٠p< با استفاده از نرم‌افزار 20SPSS تحلیل شد.


نتایج: نتایج نشان داد که بین دو گروه کنترل و تجربی در تغییرات ترکیبات بدن، چربی‌های خون و سطوح مولکول چسبان عروقی تفاوت معناداری مشاهده نشد (005/0p>).


نتیجه‌گیری: به‌نظر می‌رسد 10 هفته تمرین ترکیبی به‌منظور کاهش سطوح VCAM-1 و چربی‌های خون کافی نباشد و نیاز به تحقیقات بیشتری در این زمینه می‌باشد.

کلیدواژه‌ها


عنوان مقاله [English]

Effect of ten-week combined exercise (aerobic-resistance) on vascular adhesion molecules and lipid profile in overweight and obese women

چکیده [English]

Background and Objective: Adhesion molecules play an important role in the pathogenesis of atherosclerosis. The aim of this study was to assess the effect of combined exercise on vascular adhesion molecules and lipid profile in obese and overweight women.


Materials and Methods: Eighteen women participated in this study (age: 39.33±7.7 years; weight: 76.57±5.19 kg). The subjects were randomly divided into two groups: exercise and control groups. The exercise protocol included: aerobic exercise (60-75% Maximum Heart Rate) and resistance exercise program (two sets with 10-12 repetitions and with an intensity of 40-60% of maximum repetition and rest time of 60-90 seconds) for 10 weeks 3 times a week. During the study, the control group received no intervention. At the beginning and 48 hours after exercise, blood samples were taken for measurement of adhesion molecules and lipids. Data was analyzed with independent t-test with SPSS16 (p<0.05).


Results: Test results showed that there were no differences in anthropometric indices, vascular cell adhesion molecule-1 and lipid levels between control and experimental groups (p>0.05).


Conclusion: It seems that 10-week combined exercise in order to reduce VCAM-1 levels and lipid profiles is insufficient and more research is needed in this area.

کلیدواژه‌ها [English]

  • Combined exercise
  • Vascular adhesion molecule
  • Overweight
  • Obese
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