تاثیر هشت هفته تمرین ترکیبی (مقاومتی-استقامتی) و مصرف امگا 3 بر سطوح فتوئین A و پروفایل متابولیک در زنان سالمند چاق

نویسندگان

1 گروه تربیت بدنی و علوم ورزشی، واحد علوم و تحقیقات، دانشگاه آزاد اسلامی، تهران، ایران

2 گروه تربیت بدنی و علوم ورزشی، واحد شهر قدس، دانشگاه آزاد اسلامی، تهران، ایران

چکیده

مقدمه و هدف: فتوئین A توسط بافت­های مختلف بویژه کبد و بافت چربی ترشح می­شود و بر عملکرد اندام­های مختلف بدن تاثیر می­گذارد. هدف از پژوهش حاضر بررسی تاثیر هشت هفته تمرین ترکیبی (مقاومتی-استقامتی) و مصرف امگا 3 بر سطوح فتوئین A و پروفایل متابولیک در زنان سالمند چاق بود.
مواد و روش‌ها: در یک پژوهش نیمه تجربی، 40 زن سالمند چاق (میانگین سنی 83/3±74/65 سال، شاخص توده بدن kg.m2 00/5±1/32) در چهار گروه دارونما، امگا3، تمرین و تمرین+امگا3 تقسیم­بندی شدند. برنامه تمرین ترکیبی (مقاومتی-استقامتی) به مدت هشت هفته و سه جلسه در هفته اجرا شد و هر جلسه تمرین ترکیبی مشتمل بر تمرین مقاومتی و استقامتی بود. آزمودنی­ها در گروه امگا3 و تمرین+امگا3، روزانه 2000 میلی­گرم امگا3 مصرف کردند. خونگیری در دو مرحله پیش آزمون و پس آزمون (دو روز بعد از آخرین جلسه تمرین ترکیبی) انجام گرفت و سطوح فتوئین A به روش الایزا اندازه­گیری شد. تجزیه و تحلیل داده­ها با آزمون آنالیز کوواریانس انجام شد.
 نتایج: سطوح نتایج مطالعه حاضر نشان داد که سطوح فتوئین A در گروه تمرین و تمرین+امگا3 در مقایسه با گروه دارونما و گروه امگا3 به صورت معناداری کاهش یافته است (001/0>p < /span>) که این تغییرات با بهبود نیمرخ لیپیدی همراه بود.
 نتیجه­ گیری: احتمالاً کاهش سطوح فتوئین A بخشی از مسیر تاثیرگذاری مثبت تمرین ترکیبی در بهبود پروفایل متابولیک زنان سالمند چاق می­باشد.
 

کلیدواژه‌ها


عنوان مقاله [English]

The effect of eight-week combined exercise training (resistance-endurance) and Omega-3 ingestion on the levels of fetuin-A and metabolic profile in obese elderly women

نویسندگان [English]

  • Farnaz Dadash Nejad 1
  • Mandana Gholami 1
  • Shahram Soheili 2
چکیده [English]

Background and Objective: Fetuin A is secreted by different tissues including liver and adipose tissue and affects the function of different body tissues. The aim of the present study was to investigate the effect of eight-week combined exercise training (resistance-endurance) and Omega-3 ingestion on the levels of fetuin-A and metabolic profile in elderly obese women.
 
Materials and Methods: In a semi-experimental research, 40 elderly obese women (average age of 65.74±3.83 years old, body mass index 32.5±1.0 kg.m2) were assigned to four groups including placebo, Omega3, training and training+Omega3 groups. Combined exercise training (resistance-aerobic) was conducted for eight weeks and three session per week and each combined training session consists of resistance and aerobic training. The subjects in Omega3 and training+Omega3 groups consumed daily 2000 mg of Omega 3. Blood sampling was conducted in pre and post (two days after last combined training session) stages and fetuin A level was measured by Elisa method. Data was analyzed by covariance test.
 
Results: Present study results indicated that fetuin A level significantly decreases in training and training+Omega3 group compared to placebo and Omega3 groups (p<0.001) and these changes were associated with improvement of lipid profiles.
 
Conclusion: Probably, a decrease in fetuin A level is part of positive effectiveness pathway of combined training in improving metabolic profile in elderly obese women.
 

کلیدواژه‌ها [English]

  • Elderly
  • Combined training
  • Fetuin A
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