تأثیر چهار هفته تمرین هوازی و مکمل‌دهی روغن سیاه‌دانه بر سطوح سرمی مالون دی آلدهید و ظرفیت آنتی‌اکسیدانی تام دختران جوان غیرفعال

نوع مقاله : مقاله پژوهشی

نویسندگان

1 گروه علوم ورزشی، دانشگاه قم، قم، ایران

2 گروه فیزیولوژی ورزشی، دانشگاه قم، قم، ایران

3 گروه آمار، دانشگاه قم، قم، ایران

چکیده

مقدمه و هدف: مداخلات تمرینی و مصرف برخی مکمل‌ها می‌تواند منجر به تغییراتی در سیستم آنتی‌اکسیدانی و استرس اکسیداتیو عضلات اسکلتی شود. بر این اساس پژوهش حاضر، به بررسی و مطالعه اثر توأمان چهار هفته مکمل‌دهی روغن سیاه‌دانه و تمرین هوازی بر سطوح سرمی مالون دی آلدهید و ظرفیت آنتی‌اکسیدانی تام دختران غیرفعال پرداخت.
مواد و روش ها: بدین منظور، تعداد 40 نفر از زنان جوان غیرفعال دارای شرایط ورود به مطالعه دانشگاه قم با میانگین سنی: 51/4 ± 23/22 و 21/4 ± 46/25 BMI: با پرکردن رضایت‌نامه کتبی در پژوهش پیش‌رو شرکت کردند. آزمودنی‌ها به‌صورت تصادفی به چهار گروه کنترل (9 نفر)، تمرین + دارونما (10 نفر)، مکمل (10 نفر) و تمرین + مکمل (11نفر) تقسیم شدند. گروه‌های تمرین هوازی چهار هفته تمرینات هوازی ایروبیک را با شدت 50 تا 80 درصد ضربان قلب بیشینه را سه جلسه در هفته انجام دادند، همچنین گروه‌های مکمل روغن سیاه‌دانه روزانه یک کپسول1000 میلی‌گرم را در روز بعد از وعده ناهار دریافت کردند. نمونه‌های خونی برای اندازه‌گیری سطح سرمی مالون آلدهید و ظرفیت آنتی‌اکسیدانی تام در دو مرحله قبل و 24 ساعت بعد از آخرین جلسه تمرین در شرایط ناشتا از سیاهرگ زند اعلا جمع‌آوری شدند. تحلیل آماری به‌وسیله آزمون‌های t زوجی و تحلیل کوواریانس در سطح معنی‌داری 05/0>P انجام گرفت.
نتایج: نتایج بین‌گروهی نشان داد که بین گروه هوازی با دو گروه مکمل (03/0= P) و مکمل+ تمرین (03/0=P) در مقادیر TAC سرمی کاهش معنی‌داری وجود دارد، همچنین کاهش معنی‌دار پس‌آزمون نسبت به پیش‌آزمون در مقادیر درون‌گروهی غلظت سرمی MDA در گروه مکمل (03/0=P) نشان داده شد.
نتیجه‌گیری: با توجه به نتایج به‌دست‌آمده می‌توان گفت تمرینات هوازی و مکمل‌دهی سیاه‌دانه منجر به کاهش ظرفیت آنتی‌اکسیدان تام می‌شود، و تأثیری بر شاخص اکسیداتیوی ندارد.

کلیدواژه‌ها

عنوان مقاله [English]

Simultaneous effect of four weeks of Nigella sativa oil supplementation and aerobic exercise on serum levels of malondialdehyde and total antioxidant capacity in inactive young women

نویسندگان [English]

  • Ali Ghasemi Kahrizsangi 1
  • Zahra Hajikhodadadi 2
  • Zahra Abedin Zadeh 2
  • Mohsen Salehi 3
1 Sport Sciences Department, University of Qom, Qom, Iran
2 Sports Physiology Department, Qom University, Qom, Iran
3 Department of Statistics, Faculty of Science, University of Qom, Qom, Iran
چکیده [English]

Background and Objective: Exercise interventions and consumption of some supplements can lead to changes in the antioxidant system and oxidative stress of skeletal muscles. Based on this, the present study investigated the effect of four weeks of Nigella sativa oil supplementation and aerobic exercise on the serum levels of malondialdehyde and the total antioxidant capacity of inactive young women.
Materials and Methods: For this purpose, 40 inactive young women with an average age of 22.23 ± 4.51 years and BMI of 25.46 ± 4.21 participated in the research. Prior to the treatment, they filled out a written consent form. Then, the subjects were randomly divided into four groups: control (N=9), exercise + placebo (N=10), supplement (N=10), and exercise + supplement (N=11). The aerobic exercise groups performed four weeks of aerobic exercise with an intensity of 50% to 80% of the maximum heart rate, three sessions a week. Also, the Nigella sativa oil supplement groups received 1000 mg of its capsule per day after lunch. Blood samples were collected to measure the serum level of malondialdehyde and total antioxidant capacity in two stages before and after 24 hours of the last training session in fasting conditions from antecubital vein. Statistical analysis was performed by paired t-tests and the analysis of covariance at a significance level of P<0.05.
Results: Results showed that there is a significant decrease in total antioxidant capacity values between the aerobic group with the two supplement groups (P=0.03) and supplement + exercise (P=0.03). Also, a significant decrease was shown after the test as was compared to the pre-test in the within-group values of malondialdehyde serum concentration in the supplement group (P=0.03).
Conclusion: According to the results, we conclude that the aerobic exercises and Nigella sativa supplementation leads to a decrease in the total antioxidant capacity and it has no effect on the oxidative index.

کلیدواژه‌ها [English]

  • Aerobic exercises
  • Malondialdehyde
  • Total antioxidant capacity
  • Nigella sativa supplement
  • Inactive women

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دانشور پزشکی
دوره 31، شماره 6 - شماره پیاپی 169
بهمن و اسفند 1402
صفحه 14-25

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