Background
and Objective: Visfatin is a
recently discovered adipokine. Previous studies have shown a direct
relationship between plasma visfatin levels and type 2 diabetes mellitus. The current study was conducted to
investigate the effect of aerobic exercise on
plasma level of visfatin in type 2 diabetic men treated with metformin. Materials
and Methods: Thirty-six men with type 2
diabetes who consumed metformin (age 46.08 ± 3.08 years, BMI 30.1± 2.32 kg/m2)
volunteered to participate in this study. Subjects were randomly assigned in 2
groups. In this respect, 18 subjects were in the aerobic exercise group (3 days
per week, 35 to 50 min per day, 40-55% heart rate reserve) and 18 subjects in
the control group. Fasting plasma visfatin, insulin, glucose and HbA1c
concentrations were measured
before and after 8 weeks of exercise in these diabetic patients. For analysis
of data, repeated measures ANOVA was used. Results: The findings showed that plasma visfatin level, insulin, glucose,
HbA1c, BMI, WHR and body fat percentage significantly decrease in
aerobic exercise group as compared to control group (p < 0.05). The peak rate
of oxygen consumption (vo2 peak) significantly increased in aerobic exercise
group as compared to control group (p < 0.05). Conclusion: The present study showed that decreased plasma visfatin level induced
by aerobic exercise is most likely the result of improving glycemic status in
type 2 diabetes patients treated with metformin.
azimi, S. M., marefati, H., yousefzadeh, G., & mohajeri, M. (2012). The effect of aerobic exercise on plasma visfatin levels in men with type 2diabetes treated with metformin. Daneshvar Medicine, 20(4), 17-24.
MLA
seyed mohammad azimi; hamid marefati; gholamreza yousefzadeh; majid mohajeri. "The effect of aerobic exercise on plasma visfatin levels in men with type 2diabetes treated with metformin". Daneshvar Medicine, 20, 4, 2012, 17-24.
HARVARD
azimi, S. M., marefati, H., yousefzadeh, G., mohajeri, M. (2012). 'The effect of aerobic exercise on plasma visfatin levels in men with type 2diabetes treated with metformin', Daneshvar Medicine, 20(4), pp. 17-24.
VANCOUVER
azimi, S. M., marefati, H., yousefzadeh, G., mohajeri, M. The effect of aerobic exercise on plasma visfatin levels in men with type 2diabetes treated with metformin. Daneshvar Medicine, 2012; 20(4): 17-24.
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