Document Type : Original Article
Authors
1
MSc in Sport Physiology, Faculty of Sport Sciences, Hakim Sabzevari University, Sabzevar, Iran
2
Department of Physical Education and Sport Sciences, Faculty of Sport Sciences, Hakim Sabzevari University, Sabzevar, Iran
3
Professor in Sport Physiology, Faculty of Sport Sciences, Hakim Sabzevari University, Sabzevar, Iran
Abstract
Background and Objective: Obesity and dyslipidemia, which are often accompanied by chronic inflammation, pose a major public health challenge. This necessitates investigating effective combined exercise and nutritional interventions to improve metabolic and inflammatory parameters. This study aimed to compare the effect of eight weeks of Moderate-Intensity Interval Training (MIIT), with and without Spirulina supplementation, on the levels of monocyte chemoattractant protein-1, interleukin-10, and the lipid profile of obese women.
Materials and Methods: In this semi-experimental study, 20 obese women were randomly divided into two groups: Moderate-Intensity Interval Training (MIIT) with Spirulina supplementation, and MIIT) with Placebo. The intervention lasted eight weeks and included three training sessions per week. Data analysis utilized repeated measures Analysis of Variance (ANOVA) to compare changes between and within groups.
Results; The time $\times$ group interaction changes were not significant for the variables MCP-1, IL-10, total cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL), and triglycerides. Within-group changes showed a significant decrease in MCP-1 in the exercise and supplement group, while IL-10 levels significantly increased in the exercise and supplement group at the end of the intervention period. Furthermore, only the exercise and Spirulina supplement group demonstrated significant reductions in total cholesterol, low-density lipoprotein, and triglycerides.
Conclusion: The findings indicate that eight weeks of Spirulina supplementation, when combined with Moderate-Intensity Interval Training, is highly effective in modulating the exercise-induced inflammatory response and improving the lipid profile.
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