Daneshvar Medicine

Daneshvar Medicine

The effect of six weeks of high intensity interval training on the serum levels of oxidative stress parameters of athletics athletes in Yasouj city

Document Type : Original Article

Authors
Sadegh Khademi 1
Aabas Salehikia 1
omid mohammaddoost 1
Mohammad Ali Mirshekar 2
1 Faculty of Educational Sciences and Psychology, University of Sistan and Baluchistan, Zahedan, Iran
2 Department of Physiology, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
10.22070/daneshmed.2024.19763.1564
Abstract
Objective:The aim of this study was to investigate the effect of 6 weeks of high intensity interval training (HIIT) on the serum levels of oxidative stress parameters(malondialdehyde, superoxide dismutase and catalase) of athletics athletes in Yasouj city
Materials and Methods: In this quasi-experimental study, the statistical population was male track and field athletes in Yasuj, excluding female endurance athletes; among them, 30 female sprinters, throwers, and jumpers in the age range of 22-32 years were purposefully selected as a statistical sample and randomly divided into 2 groups of 15 (HIIT training and control).HIIT training protocol was performed at an intensity of 90% of maximum heart rate for 6 weeks (3 sessions per week). Blood samples were taken from the subjects before and after training and kits were used to measure malondialdehyde, superoxide dismutase, and catalase. Paired t-test was used to determine intra-group changes, and covariance test was used to compare between groups at a significance level of p<0.05 (p<0.05). The obtained data were analyzed with SPSS-25.
Results: The findings showed that serum levels of malondialdehyde, superoxide dismutase, and catalase in the training group after six weeks of HIIT training were significantly different from the pre-test (p=0.00). Also, serum levels of these variables were significantly different between the training group and the control group at the post-test (p=0.01).
Conclusion: The results of this study showed that in order to reduce oxidative stress and improve the antioxidant capacity of runners, HIIT exercises can be used in runners' training program.
Keywords
High-intensity interval training
Malondialdehyde
Superoxide dismutase
Catalase
Track and field athletes
  1. Afrondeh R, Khaja Landi M, Mohammadi R. Comparison of the effect of 6 weeks of aerobic training on catalase and malondialdehyde enzyme activity in heart tissue of healthy and diabetic male Wistar rats treated with streptozotocin. Urmia Medical Journal 2018;30(5):37-346.
  2. Kassaee SM, Goodarzi MT, Oshaghi EA. Antioxidant, antiglycation and anti-hyperlipidemic effects of Trigonella foenum and Cinnamon in type 2 diabetic rats. Jundishapur Journal of Natural Pharmaceutical Products 2018;13(1):e38414. [In Persian]
  3. Jehani GR, Firouz Rai M, Mateen Homai H, Tarvardizadeh B, Azarbaijani MA, Motheghi GR, et al. The effect of regular and continuous sports training on the activity of erythrocyte antioxidant enzymes and oxidative stress in young soccer players. Journal of Iran University of Medical Sciences 2010;17(1):74. [In Persian]
  4. Martinovic J, Dopsaj V, Kotur-Stevuljevic J, Dopsaj M, Vujovic A, Stefanovic A, et al. Oxidative stress biomarker monitoring in elite women volleyball athletes during a 6-week training period. The Journal of Strength & Conditioning Research 2011;25(5):1360-7.
  5. Wang D, Wang J, Liu Y, Zhao Z, Liu Q. Roles of Chinese herbal medicines in ischemic heart diseases (IHD )by regulating oxidative stress. International Journal of Cardiology 2016;220:314-9.
  6. Ahmadi Kakavandi M, GHayseri F. The effect of increasing resistance training on malondialdehyde concentration and superoxide desmutase enzyme activity in inactive elderly women. Journal of Paramedical Faculty of Tehran University of Medical Sciences (Piyavard Salamat) 2018;13(2):151-9. [In Persian]
  7. Shiravand F, Valipour V, Abbasi Moghadam M. The effect of 8 weeks of high-intensity circuit training on the serum levels of catalase, malondialdehyde and maximal oxygen consumption in women who survived breast cancer. Faiz Scientific-Research Bi-Monthly 2018;23(4):398-406.
  8. Nurshahi M, Ebrahim K, Taheri Chadorneshin H. The effect of vitamin E supplementation on the response of angiogenic factor to inhibitory activity. Research in Sports Science, 2010. [In Persian]
  9. Parolini M, Iacobuzio R, De Felice B, Bassano B, Pennati R, Saino N. Age-and sexdependent variation in the activity of antioxidant enzymes in the brown trout (Salmo trutta). Fish Physiology and Biochemistry 2019;45(1):145-154.
  10. Ebrahimi E, Ramzan Pour MR, Hijazi M. Comparison of the effect of eight weeks of aerobic exercise and consumption on antioxidant enzymes in vitamin C type 2 diabetic men. Horizon Journal of Medical Sciences 2018; 24(2):104-12. [In Persian]
  11. Singh Z, Karthigesu IP, Singh P ,Rupinder K. Use of malondialdehyde as a biomarker for assessing oxidative stress in different disease pathologies: a review. Iranian Journal of Public Health 2014;43(3):7-16.
  12. Deng H, Wen Q, Luo Y, Huang Y, Huang R. Influence of different extracts from persimmon leaves on the antioxidant activity in diabetic mice. Journal of Central South University Medical Sciences 2012;37(5):469-73.
  13. Han-Yao Huang, Lawrence J Appel, Kevin D Croft, Edgar R Miller, III, Trevor A Mori and Ian B Puddey. Effects of vitamin C and vitamin E on in vivo lipid peroxidation: results of a randomized controlled trial1 2002;2,3.
  14. Gupt AM, Kumar M, Sharma RK, Misra R, Gup A. Effect of moderate aerobic exercise training on pulmonary functions and Its correlation with the antioxidant status. National Journal of Medical Research 2015;5(2):136-9.
  15. Wu G, Fang Y Z, Yang S, Lupton JR, Turner ND. Glutathione metabolism and its implications for health. Journal of Nutrition  2004;134(3):489–
  16. Delwing-de Lima D, Ulbricht A, Werlang-Coelho C, Delwing-Dal Magro D, Joaquim VHA, Salamaia EM, et al. Effects of two aerobic exercise training protocols on parameters of oxidative stress in the blood and liver of obese rats. Journal of Physiological Sciences 2018;68(5):699-706.
  17. Freitas DA, Rocha-Vieira E, Soares BA, Nonato LF, Fonseca SR, Martins JB, et al. High intensity interval training modulates hippocampal oxidative stress, BDNF and inflammatory mediators in rats. Physiol Behav 2018;184:6-11.
  18. Parastesh M, Yousefvand Z, Moghadasi S. Comparison of the effect of moderate-intensity interval training (MICT) and high-intensity interval training (HIIT) on testicular structure, serum level of malondialdehyde and total antioxidant capacity of male diabetic rats. Daneshvar Medicine 2020;27(2):27-40. [In Persian]
  19. Rai S, Chowdhury A, Reniers RLEP, Wood SJ, Lucas SJE, Aldred S. A pilot study to assess the effect of acute exercise on brain glutathione. Free radical research 2018;52(1):57-69.
  20. Peterson J, Dwyer J, Adlercreutz H, Scalbert A, Jacques P, McCullough ML. Dietary lignans: physiology and potential for cardiovascular disease risk reduction. Nutrition Reviews 2010;68(10):571- 603.
  21. Jesudason DR, Dunstan K, Leong D, Wittert GA. Macrovascular risk and diagnostic criteria for type 2 diabetes implications for the use of FPG and HbA1c for cost-effective screening. Diabetes Care 2003;26(2):485-90.
  22. Valadoa A, Tavaresb P, Pereirac L, Ribeiroa F. Anaerobic exercise and oxidative stress effect of the intense exercise on nitric oxide and malondialdehyde. Int Conference on Cellular &Molecular Biology-Biophysics & Bioengineering; Greece 2007;3(2):26-8.
  23. Woodside J W, Young I S, Yarnell . Antioxidants, but not B-group vitamins, increase the resistance of low-density lipoprotein to oxidation: a randomized, factorial design, placebo-controlled trial. Atherosclerosis 1999;144:419-27.
  24. Mogharabian N, Khaksari M, Eslami T, Ahmadian Chashmi N, Khastar H. Evaluation of Protective Effects of Usnic Acid in Cisplatin Induced Nephrotoxicity in Rats. Journal of Knowledge & Health in Basic Medical Sciences 2020;15(2):10-15. [In Persian]
  25. Fisher-Wellman K, Bloomer RJ. Acute exercise and oxidative stress: a 30 year history. Nicotine & Tobacco Research 2009;11(1):3-11.
  26. Leaf-nosed bat. Encyclopædia Britannica: Encyclopædia Britannica Online; 2009.
  27. Modir M, Daryanoosh F, Mohamadi M, Firouzmand H. The effects of short and middle times aerobic exercise with high intensities on ingredients antioxidant in female Sprague Dawley rats. Medical Journal of Mashhad University of Medical Sciences 2014;57(3):587-95. [In Persian]
  28. Tahiri Chadorneshin H, Sahat M. The effect of two weeks of vitamin E consumption on the response of cell adhesion molecules to the inhibitory activity. Sports Biology Journal 2012;4(10):25-41. [In Persian]
  29. Suh S, Jeong IK, Kim MY, Kim YS, Shin S, Kim SS, et al. Effects of resistance training and aerobic exercise on insulin sensitivity in overweight korean adolescents: a controlled randomized trial. Diabetes & Metabolism Journal 2011;35(4):418-26.
  30. Kaneto H, Kawamori D, Matsuoka T-a, Kajimoto Y, Yamasaki Y. Oxidative stress and pancreatic β-cell dysfunction. American Journal of Therapeutics 2005;12(6):529-33.
  31. Kim HJ, Lee HJ, So B, Son JS, Yoon D, Song W. Effect of aerobic training and resistance training on circulating irisin level and their association with change of body composition in overweight/obese adults: a pilot study. Physiological research 2016;65(2):271-9.
  32. Radak Z, Zhao Z, Koltai E, Ohno H, Atalay M. Oxygen consumption and usage during physical exercise: the balance between oxidative stress and ROS-dependent adaptive signaling. Antioxidants & Redox Signaling 2013;18(10):1208-46.
  33. Rai S, Chowdhury A, Reniers RLEP, Wood SJ, Lucas SJE, Aldred S. A pilot study to assess the effect of acute exercise on brain glutathione. Free Radical Research 2018;52(1):57-69.
  34. Bogdanis GC, Stavrinou P, Fatouros IG, Philippou A, Chatzinikolaou A, Draganidis D, et al. Short-term high-intensity interval exercise training attenuates oxidative stress responses and improves antioxidant status in healthy humans. Food and Chemical Toxicology 2013;61:171-7.
  35. Souza-Silva AA, Moreira E, de Melo-Marins D, Schöler CM, de Bittencourt Jr PIH, Laitano O. High intensity interval training in the heat enhances exercise-induced lipid peroxidation, but prevents protein oxidation in physically active men. Temperature 2016;3(1):167-75.
Daneshvar Medicine
Volume 32, Issue 5 - Serial Number 174
January and February 2025
Pages 67-76