Daneshvar Medicine

Daneshvar Medicine

Effects of four-week aerobic training, caloric restriction and vitamin D supplementation on serum BDNF levels and body composition in overweight and obese women

Document Type : Original Article

Authors
Negisa Farhangi 1
Afshar Jafari 2
Ebrahim Akhtari 3
Ali Zarghami Khameneh 1
1 Department of Exercise Physiology, Faculty of Physical Education and Sport Science , University of Tabriz, Tabriz, Iran
2 Department of Biological Sciences in Sport and Health, Shahid Beheshti University, Tehran, Iran
3 Tuberculosis and Lung Diseases Research Center, Tabriz University of Medical Science, Tabriz, Iran
10.22070/daneshmed.2022.14720.1097
Abstract
Background and Objective: Obesity is a low-grade systemic inflammatory condition that is closely associated with many chronic diseases. Therefore, the purpose of present study was to determine the effect of four-week aquatic aerobic training with and without caloric restriction and vitamin D supplementation on brain-derived neurotrophic factor (BDNF) serum concentrations and body composition in overweight and obese women.
Materials and Methods: 40 overweight volunteer women (30-50 years old and BMI 35-30 kg.m2) were randomly divided into four homogeneous groups; (aerobic training: AT, aerobic training with Calorie restriction: AT+CR, aerobic training with supplementation: AT+VD, aerobic training with caloric restriction and supplementation; AT+CR+VD). Training intensity was %55-85 of reserve heart rate and all subjects participated in training for one month and three days a week. Body composition and blood samples were collected before and after the training period to determine the serum levels of BDNF. Data were analyzed by one-way ANOVA and Bonferroni's post-hoc test at α<0.05.
Results: According to data, body composition indexs decreased significantly in all groups (P<0.05). Also, the level of BDNF in all groups was significantly higher than pre-test, while this increase was statistically significant only in the-AT+RC+VD- group (P=0.012).
Conclusion: Combination of aerobic exercise with caloric restriction and vitamin D supplementation has seemingly more cumulative effects compared to each of variables alone and it might be more effective therapeutic method to improve BDNF levels and body composition.
Keywords
Aerobic training
Calorie restriction
Vitamin D
Brain drived-neurotrophic factor
Obesity
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Daneshvar Medicine
Volume 30, Issue 1 - Serial Number 158
May and June 2022
Pages 12-26