Effects of four-week aerobic training, caloric restriction and vitamin D supplementation on serum BDNF levels and body composition in overweight and obese women

Document Type : Original Article

Authors

1 Department of Exercise Physiology, Faculty of Physical Education and Sport Science , University of Tabriz, Tabriz, Iran

2 Department of Biological Sciences in Sport and Health, Shahid Beheshti University, Tehran, Iran

3 Tuberculosis and Lung Diseases Research Center, Tabriz University of Medical Science, Tabriz, Iran

Abstract

Background and Objective: Obesity is a low-grade systemic inflammatory condition that is closely associated with many chronic diseases. Therefore, the purpose of present study was to determine the effect of four-week aquatic aerobic training with and without caloric restriction and vitamin D supplementation on brain-derived neurotrophic factor (BDNF) serum concentrations and body composition in overweight and obese women.
Materials and Methods: 40 overweight volunteer women (30-50 years old and BMI 35-30 kg.m2) were randomly divided into four homogeneous groups; (aerobic training: AT, aerobic training with Calorie restriction: AT+CR, aerobic training with supplementation: AT+VD, aerobic training with caloric restriction and supplementation; AT+CR+VD). Training intensity was %55-85 of reserve heart rate and all subjects participated in training for one month and three days a week. Body composition and blood samples were collected before and after the training period to determine the serum levels of BDNF. Data were analyzed by one-way ANOVA and Bonferroni's post-hoc test at α<0.05.
Results: According to data, body composition indexs decreased significantly in all groups (P<0.05). Also, the level of BDNF in all groups was significantly higher than pre-test, while this increase was statistically significant only in the-AT+RC+VD- group (P=0.012).
Conclusion: Combination of aerobic exercise with caloric restriction and vitamin D supplementation has seemingly more cumulative effects compared to each of variables alone and it might be more effective therapeutic method to improve BDNF levels and body composition.

Keywords

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Daneshvar Medicine
Volume 30, Issue 1 - Serial Number 158
May and June 2022
Pages 12-26

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