The effect of resistance training intensity and volume on serum vaspin concentration and insulin resistance index in adult male rats

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Abstract

 Background and Objective: Vaspin (visceral
adipose tissue-derived serpin) was identified as a potential insulin
sensitizing adipokine. The purpose of this study was to investigate the effect
of resistance training intensity and volume on serum vaspin concentration and
insulin resistance index.    Materials and Methods: Thirty two male Wister rats (287 ±
24 g) were randomly divided into four groups: (1) control, (2) trained with low
intensity, (3) trained with moderate intensity, and (4) trained with high
volume in moderate intensity. The resistance training consisted of climbing a
ladder carrying a load suspended from the tail. After 4 weeks resistance
training, serum glucose, insulin, and vaspin concentrations were measured, and
insulin resistance index (HOMA-IR) was calculated.    Results: Serum vaspin concentrations were lower in trained
groups compared with control group. Trained groups had lower serum insulin
concentrations and insulin resistance index than control group. The lowest
serum insulin concentration and insulin resistance index were found in high
volume in moderate intensity group.   Conclusion: This study indicated that resistance training
could decrease serum vaspin and insulin concentrations as well as insulin
resistance index. The volume of resistance training is an effective factor to
improve insulin sensitivity. 

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