The effect of aerobic training on serum levels of ghrelin and leptin in middle-aged men

Authors

Abstract

 Background and Objective: Ghrelin and leptin are two
hormones involved in the regulation of energy balance and obesity. The
objective of this study was to investigate the effect of a course of aerobic
training on serum levels of ghrelin and leptin in the middle-aged men.
Materials and    Materials and Methods: Twenty middle-aged volunteered
males were randomly divided into experimental (n=10) and control (n=10) groups. Aerobic training protocol
consisted of 3 sessions per week for 10 weeks. Each training session was a slow
running trial with intensity of 65 to 75 percent of maximal heart rate for a
period of 10 minutes. To follow the principle of overload, half-a-minute was
added to each session, so that, at the last session the running time reached to
25 minutes. Before and after the training
period, blood sampling was performed. Data were analyzed using independent t-test.    Results: There was no significant difference in serum
levels of ghrelin and leptin between control and experimental groups (p < 0.05). However, aerobic training significantly reduced
body mass index, body weight, waist to hip ratio, and body fat percent and
significantly increased the lean body weight and maximum oxygen uptake.    Conclusion: It can be deduced that 10-week aerobic training
has no beneficial effect on serum levels of ghrelin and leptin in the
middle-aged men. However, to achieve more conclusive results, further
investigation is warranted. 

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