Shahed UniversityDaneshvar Medicine2716-972321220130622Comparison of nitric oxide secretion by human adipose tissue-derived mesenchymal stem cells in healthy pregnant women and those with preeclampsiaComparison of nitric oxide secretion by human adipose tissue-derived mesenchymal stem cells in healthy pregnant women and those with preeclampsia1101569FAEnsie SadatMirsharifSakineMoaied MohseniEisaSalehiSeyed MahmoudHashemiToobaGhazanfari0000-0002-1049-7095Journal Article20200926 Background and Objective: Preeclampsia is one of the
most common
complications
during pregnancy
that occurs after 20th weeks of pregnancy in women with normal blood
pressure. The pathophysiology of this disease is unknown. Due
to changes in serum level of nitric oxide in women with preeclampsia and also
the important role of mesenchymal stem cells in the secretion of nitric oxide
as an immunoregulator, in this study, we aimed to evaluate the level of nitric
oxide in secretions of adipose tissue-derived mesenchymal stem cells
in women with normal pregnancy and patients with preeclampsia. Materials and Methods: Subcutaneous adipose tissue
of 10
preeclamptic patients and 10 healthy pregnant women was collected during cesarean operation.
After
isolation and
proliferation of mesenchymal
stem cells, capablity
of their differentiation
and their immunophenotyping charactetistics were assessed. Then,
their release
of nitric oxide
was evaluated
using Griess
method. Results: Stem cells isolated from adipose
tissue in both groups differentiated into osteocyte and adipocytes. Flow-cytometric
analysis
showed the
expression of
the markers
CD90, CD73 CD44
and
CD105
and lack of
expression of the markers
CD-14, CD34,
CD45 and
HLA-DR
in both
groups.
No significant
change
was observed for
the level
of nitric
oxide secretion in
both groups. Conclusion: The present results
suggest that nitric oxide secreted by mesenchymal stem cells do not have a
significant contribution in variation of serum level of this factor and
possibly do not play a role in the pathology of preeclampsia. However, such
study with a higher sample size is suggested. Results: Stem cells isolated from adipose
tissue in both groups differentiated into osteocyte and adipocytes. Flow-cytometric
analysis
showed the
expression of
the markers
CD90, CD73 CD44
and
CD105
and lack of
expression of the markers
CD-14, CD34,
CD45 and
HLA-DR
in both
groups.
No significant
change
was observed for
the level
of nitric
oxide secretion in
both groups. Conclusion: The present results
suggest that nitric oxide secreted by mesenchymal stem cells do not have a
significant contribution in variation of serum level of this factor and
possibly do not play a role in the pathology of preeclampsia. However, such
study with a higher sample size is suggested. Background and Objective: Preeclampsia is one of the
most common
complications
during pregnancy
that occurs after 20th weeks of pregnancy in women with normal blood
pressure. The pathophysiology of this disease is unknown. Due
to changes in serum level of nitric oxide in women with preeclampsia and also
the important role of mesenchymal stem cells in the secretion of nitric oxide
as an immunoregulator, in this study, we aimed to evaluate the level of nitric
oxide in secretions of adipose tissue-derived mesenchymal stem cells
in women with normal pregnancy and patients with preeclampsia. Materials and Methods: Subcutaneous adipose tissue
of 10
preeclamptic patients and 10 healthy pregnant women was collected during cesarean operation.
After
isolation and
proliferation of mesenchymal
stem cells, capablity
of their differentiation
and their immunophenotyping charactetistics were assessed. Then,
their release
of nitric oxide
was evaluated
using Griess
method. Results: Stem cells isolated from adipose
tissue in both groups differentiated into osteocyte and adipocytes. Flow-cytometric
analysis
showed the
expression of
the markers
CD90, CD73 CD44
and
CD105
and lack of
expression of the markers
CD-14, CD34,
CD45 and
HLA-DR
in both
groups.
No significant
change
was observed for
the level
of nitric
oxide secretion in
both groups. Conclusion: The present results
suggest that nitric oxide secreted by mesenchymal stem cells do not have a
significant contribution in variation of serum level of this factor and
possibly do not play a role in the pathology of preeclampsia. However, such
study with a higher sample size is suggested. Results: Stem cells isolated from adipose
tissue in both groups differentiated into osteocyte and adipocytes. Flow-cytometric
analysis
showed the
expression of
the markers
CD90, CD73 CD44
and
CD105
and lack of
expression of the markers
CD-14, CD34,
CD45 and
HLA-DR
in both
groups.
No significant
change
was observed for
the level
of nitric
oxide secretion in
both groups. Conclusion: The present results
suggest that nitric oxide secreted by mesenchymal stem cells do not have a
significant contribution in variation of serum level of this factor and
possibly do not play a role in the pathology of preeclampsia. However, such
study with a higher sample size is suggested. https://daneshvarmed.shahed.ac.ir/article_1569_655ea4bd3b5736d88afc30c9212ccddf.pdfShahed UniversityDaneshvar Medicine2716-972321220130622Factors associated with preventive behaviors of hepatitis B among high school girls using the health belief modelFactors associated with preventive behaviors of hepatitis B among high school girls using the health belief model11221570FARezvanYazdaniFereshtehZamani-AlavijehMitraKheiriatAmirShafieeMohammadArjmandzadeganJournal Article20200926 Background and
Objective: Hepatitis
B prevention is a very important issue in the young women, since it can
transfer from mother to infant. This study was aimed to determine factors
associated with preventive behaviors of hepatitis B among the high school girls
during the academic year 2005-2006 in the Arak, Iran. Materials and Methods: This
cross-sectional study was performed in five high schools in the Arak city. A
total of 590 students from the first and second grades, who agreed to take part
in the study, enrolled using a cluster sampling method. The data were collected
by a questionnaire, including constructs of perceived severity (15 items),
perceived susceptibility (eight items), perceived barriers and benefits (seven
items), behavioral intention
(10 items), and self-efficiency (two items). Results: The
results showed that the mean age of students was 16.27 ± 0.72 years. Only 5.4%
of students had received the hepatitis B vaccination in three intervals and
more than one quarter (28.1%) of them were never used their personal equipment
when they have gone to the barber salon. The constructs of perceived barriers
(p=0.001), perceived susceptibility (p=0.022) and self-efficacy (p=0.001) were
significantly associated with preventive behaviors of hepatitis B. The perceived
barriers (3.76±0.60) had the maximum score, while self-efficacy (2.13± 0.87)
had the minimum score. Conclusion: Due
to the low range of preventive behaviors of hepatitis B and since these
behaviors were associated with constructs of perceived barriers, perceived
susceptibility and self-efficacy, adult girls must know about real preventive
barriers of this disease and suitable ways have to be prepared to perceive the
susceptibility of this disease and developing of self-efficiency. Background and
Objective: Hepatitis
B prevention is a very important issue in the young women, since it can
transfer from mother to infant. This study was aimed to determine factors
associated with preventive behaviors of hepatitis B among the high school girls
during the academic year 2005-2006 in the Arak, Iran. Materials and Methods: This
cross-sectional study was performed in five high schools in the Arak city. A
total of 590 students from the first and second grades, who agreed to take part
in the study, enrolled using a cluster sampling method. The data were collected
by a questionnaire, including constructs of perceived severity (15 items),
perceived susceptibility (eight items), perceived barriers and benefits (seven
items), behavioral intention
(10 items), and self-efficiency (two items). Results: The
results showed that the mean age of students was 16.27 ± 0.72 years. Only 5.4%
of students had received the hepatitis B vaccination in three intervals and
more than one quarter (28.1%) of them were never used their personal equipment
when they have gone to the barber salon. The constructs of perceived barriers
(p=0.001), perceived susceptibility (p=0.022) and self-efficacy (p=0.001) were
significantly associated with preventive behaviors of hepatitis B. The perceived
barriers (3.76±0.60) had the maximum score, while self-efficacy (2.13± 0.87)
had the minimum score. Conclusion: Due
to the low range of preventive behaviors of hepatitis B and since these
behaviors were associated with constructs of perceived barriers, perceived
susceptibility and self-efficacy, adult girls must know about real preventive
barriers of this disease and suitable ways have to be prepared to perceive the
susceptibility of this disease and developing of self-efficiency. https://daneshvarmed.shahed.ac.ir/article_1570_7949e456002b28988d38185bd30e77fd.pdfShahed UniversityDaneshvar Medicine2716-972321220130622The effect of HESA-A drug on formalin-induced inflammation in ratsThe effect of HESA-A drug on formalin-induced inflammation in rats23301571FAMohsenNaseriHosseinRezaeizadehMajidAsghariParvanehMohseni MoghaddamSeyed AbbasHashemiNejadAbbasTalebi Mazrae ShahiZahraBararPourJournal Article20200926 Background and
Objective:
HESA-A is a natural compound with
herbal-marine origin that
its therapeutic
effects have
been proved in
cancer.
The present study investigated HESA-A drug effect in an inflammatory model in
rats. Materials and
Methods:
In this study, four groups of rats were used with a sample size of six in each
group. These groups were negative control (distilled water), positive control
(methylprednisolone) and treatment groups (HESA-A at dosages of 150 and 225
mg/kg). On the first day, the drugs were injected intra-peritoneally to rats.
After thirty minutes, paw volume was measured by plethysmometer and
immediately, formalin solution was injected subcutaneously into the hind paw of
rats. After an hour, inflamed paw volume was measured. In days 2-8, the
inflamed paw volume was measured and immediately drug was injected
intra-peritoneally. Results: In this study,
comparing of the HESA-225 and control groups and also HESA-225 and HESA-150
groups, indicated significant differences in days 2-8. The mean volume of rats
paw in HESA-225 group was significantly less than HESA-150 and control groups
(p < 0.05). In addition, a significant decrease in the mean volume of rats’ paw was
observed in methylprednisolone group as compared to control group in days 3-8
(p < 0.05). Conclusion: The HESA-A drug has
a chronic anti-inflammatory effect following intraperitoneal administration. Background and
Objective:
HESA-A is a natural compound with
herbal-marine origin that
its therapeutic
effects have
been proved in
cancer.
The present study investigated HESA-A drug effect in an inflammatory model in
rats. Materials and
Methods:
In this study, four groups of rats were used with a sample size of six in each
group. These groups were negative control (distilled water), positive control
(methylprednisolone) and treatment groups (HESA-A at dosages of 150 and 225
mg/kg). On the first day, the drugs were injected intra-peritoneally to rats.
After thirty minutes, paw volume was measured by plethysmometer and
immediately, formalin solution was injected subcutaneously into the hind paw of
rats. After an hour, inflamed paw volume was measured. In days 2-8, the
inflamed paw volume was measured and immediately drug was injected
intra-peritoneally. Results: In this study,
comparing of the HESA-225 and control groups and also HESA-225 and HESA-150
groups, indicated significant differences in days 2-8. The mean volume of rats
paw in HESA-225 group was significantly less than HESA-150 and control groups
(p < 0.05). In addition, a significant decrease in the mean volume of rats’ paw was
observed in methylprednisolone group as compared to control group in days 3-8
(p < 0.05). Conclusion: The HESA-A drug has
a chronic anti-inflammatory effect following intraperitoneal administration. https://daneshvarmed.shahed.ac.ir/article_1571_7bd28f15a49d5e5848d6ec70e584e625.pdfShahed UniversityDaneshvar Medicine2716-972321220130622The effect of intrathecal administration of gap junction blocker and GABAA agonist and/or antagonist on chemical pain behavioral responses in male ratThe effect of intrathecal administration of gap junction blocker and GABAA agonist and/or antagonist on chemical pain behavioral responses in male rat31401572FASiminAfshar-KargarNaserMahdavi-ShahriJournal Article20200926 Background
and Objective: GABAergic inhibitory interneurons are distributed in spinal cord
for pain sensation, so that muscimol and bicuculline (GABAA agonist
and antagonist) reduces and enhances pain, respectively. Gap junctions (Gj) are
membrane contacts for exchanging the signaling agents and small metabolites.
Using spinal administration (i.t) of carbenoxolone (Gj blockers), this study
tried to understand the Gj and spinal GABAergic system roles on chemical pain
sensation. Materials
ad Methods: Male Wistar rats (200-250 g) were divided into 8 groups (n=7). The drugs were
injected at 10 μl volume intrathecally including carbenoxolone (1nM), muscimol
(0.3 μg) and bicuculline (0.3 and 0.6 μg) individually or as a form of
co-treatment. Sub-plantar injection of 0.05 ml of 2.5% formalin was used and pain
related behaviors were recorded for 1 hour. Results: Carbenoxolone and muscimol reduced pain (p < 0.01 and p < 0.05,
respectively), and bicuculline elevated
pain (p < 0.01) induced by formalin. Carbenoxolone co-treatment with muscimol reduced
pain more than each one (p < 0.05). Administration of carbenoxolone
reduced hyperalgesia induced by bicuculline (p < 0.05). Conclusion: Muscimol
analgesic effect elevation and bicuculline hyperalgesic effect alleviation
followed by Gjs blockade might be explained when the existence of Gj is
considered between a primary inhibitory interneuron effective on a secondary
interneuron which inhibits spinal pain projection neurons. Background
and Objective: GABAergic inhibitory interneurons are distributed in spinal cord
for pain sensation, so that muscimol and bicuculline (GABAA agonist
and antagonist) reduces and enhances pain, respectively. Gap junctions (Gj) are
membrane contacts for exchanging the signaling agents and small metabolites.
Using spinal administration (i.t) of carbenoxolone (Gj blockers), this study
tried to understand the Gj and spinal GABAergic system roles on chemical pain
sensation. Materials
ad Methods: Male Wistar rats (200-250 g) were divided into 8 groups (n=7). The drugs were
injected at 10 μl volume intrathecally including carbenoxolone (1nM), muscimol
(0.3 μg) and bicuculline (0.3 and 0.6 μg) individually or as a form of
co-treatment. Sub-plantar injection of 0.05 ml of 2.5% formalin was used and pain
related behaviors were recorded for 1 hour. Results: Carbenoxolone and muscimol reduced pain (p < 0.01 and p < 0.05,
respectively), and bicuculline elevated
pain (p < 0.01) induced by formalin. Carbenoxolone co-treatment with muscimol reduced
pain more than each one (p < 0.05). Administration of carbenoxolone
reduced hyperalgesia induced by bicuculline (p < 0.05). Conclusion: Muscimol
analgesic effect elevation and bicuculline hyperalgesic effect alleviation
followed by Gjs blockade might be explained when the existence of Gj is
considered between a primary inhibitory interneuron effective on a secondary
interneuron which inhibits spinal pain projection neurons. https://daneshvarmed.shahed.ac.ir/article_1572_452bf208bf901322968557227b8f6efe.pdfShahed UniversityDaneshvar Medicine2716-972321220130622In vitro comparison of apical microleakage following canal obturation with lateral and sectional warm Gutta-percha compaction techniques in open apex teethIn vitro comparison of apical microleakage following canal obturation with lateral and sectional warm Gutta-percha compaction techniques in open apex teeth41481573FABehroozEftekharMansourJafarzadehEbrahimEiniAzitaMahjoobiJournal Article20200926 Background and
Objective: The
endodontic management of immature teeth with wide open apices has always posed
particular problems. A number of canal preparation and filling techniques have
been described such as apexification, surgery and retrograde filling, customized-cone,
and apical plug. The purpose of this study was to compare the sectional
technique microleakage in open apices with lateral compaction technique. Materials and
Methods:
Twenty seven open apex canals and twenty seven close apex canals were used in
this study. Teeth were divided into two groups. In addition to 23 experimental
teeth in each group, there were 4 positive controls and 4 negative controls.
Group1 was filled with sectional warm gutta percha and group 2 was filled with
lateral condensation technique. The extent of dye penetration was determined
with stereomicroscope and by two independent observers. The data were obtained
and then statistically analyzed with t test. Results: The mean microleakage )intra-canal dye penetration(
in group 1 (sectional)(penetration was 0.042) was not significantly different
versus group 2 (lateral) (penetration was 0.027). Conclusion: This study suggests that sectional technique
is a suitable and non-surgical method for filling gutta-percha in open apex
teeth. Background and
Objective: The
endodontic management of immature teeth with wide open apices has always posed
particular problems. A number of canal preparation and filling techniques have
been described such as apexification, surgery and retrograde filling, customized-cone,
and apical plug. The purpose of this study was to compare the sectional
technique microleakage in open apices with lateral compaction technique. Materials and
Methods:
Twenty seven open apex canals and twenty seven close apex canals were used in
this study. Teeth were divided into two groups. In addition to 23 experimental
teeth in each group, there were 4 positive controls and 4 negative controls.
Group1 was filled with sectional warm gutta percha and group 2 was filled with
lateral condensation technique. The extent of dye penetration was determined
with stereomicroscope and by two independent observers. The data were obtained
and then statistically analyzed with t test. Results: The mean microleakage )intra-canal dye penetration(
in group 1 (sectional)(penetration was 0.042) was not significantly different
versus group 2 (lateral) (penetration was 0.027). Conclusion: This study suggests that sectional technique
is a suitable and non-surgical method for filling gutta-percha in open apex
teeth. https://daneshvarmed.shahed.ac.ir/article_1573_a1afc58c6ca9540d057299ec3016d726.pdfShahed UniversityDaneshvar Medicine2716-972321220130622Detemination of functional range of peripheral vestibular system using air caloric stimulationDetemination of functional range of peripheral vestibular system using air caloric stimulation49561574FASaraMomtazFahimehHajiabolhassanFahimehHajiabolhassanFahimehHajiabolhassanSaiedFarahaniShohreJalaieJournal Article20200926 Background and Objective: Caloric method is the most important test in
evaluating the vestibular function and air caloric stimulation is the most
popular method for performing this test. As there are no standard normal
criteria for this test, the goal of this study
was to define normal criteria for different parameters of caloric test which is
a part of peripheral vestibular system test battery in Tehran University
of Medical Sciences, Iran. These parameters
include directional preponderance, unilateral weakness and slow phase velocity. Materials and
Methods:
In this cross-sectional (descriptive-analytical) study, thirty two healthy
volunteers of 20-45 years of age were included. After obtaining written
informed consent and performing basic audiologic examination, Caloric test was
performed using INC model of House Infrared/Video ENG System, USA. Its
parameters were compared between males and females and within 2 different age
groups of 20-30 and 30-45. Data were analyzed with a significant level of 0.05. Results: In the right eye,
slow phase velocity was 15.23±7.43°/s, directional preponderance was
10.49±9.28% and unilateral weakness was12.27±6.45% and these values in the left
eye were 15.94±8.25°/s, 10.45±9.09% and 12.69±7.54%, respectively. There was
not any significant difference between the two genders and between the two age
groups. Conclusion: These results
suggest the
normal values for different parameters of Caloric test and it can be used to
differentiate patients and normal subjects. As there was no statistically
significant difference between males and females and two age ranges, the same
values can be used for all of them. Background and Objective: Caloric method is the most important test in
evaluating the vestibular function and air caloric stimulation is the most
popular method for performing this test. As there are no standard normal
criteria for this test, the goal of this study
was to define normal criteria for different parameters of caloric test which is
a part of peripheral vestibular system test battery in Tehran University
of Medical Sciences, Iran. These parameters
include directional preponderance, unilateral weakness and slow phase velocity. Materials and
Methods:
In this cross-sectional (descriptive-analytical) study, thirty two healthy
volunteers of 20-45 years of age were included. After obtaining written
informed consent and performing basic audiologic examination, Caloric test was
performed using INC model of House Infrared/Video ENG System, USA. Its
parameters were compared between males and females and within 2 different age
groups of 20-30 and 30-45. Data were analyzed with a significant level of 0.05. Results: In the right eye,
slow phase velocity was 15.23±7.43°/s, directional preponderance was
10.49±9.28% and unilateral weakness was12.27±6.45% and these values in the left
eye were 15.94±8.25°/s, 10.45±9.09% and 12.69±7.54%, respectively. There was
not any significant difference between the two genders and between the two age
groups. Conclusion: These results
suggest the
normal values for different parameters of Caloric test and it can be used to
differentiate patients and normal subjects. As there was no statistically
significant difference between males and females and two age ranges, the same
values can be used for all of them. https://daneshvarmed.shahed.ac.ir/article_1574_0d4f4805c36dc6853edfa4c7e1638b48.pdfShahed UniversityDaneshvar Medicine2716-972321220130622Evaluation of the enzyme activity of aminopeptidase N (CD13) in people with high level of brucella antibodyEvaluation of the enzyme activity of aminopeptidase N (CD13) in people with high level of brucella antibody57641575FANargesDoostkhahSussanKaboudanian ArdestaniForuzandehJalilvandShohreJalaeipourRezaHajehossainiAbdolfattahSarrafnejadJournal Article20200926 Background and Objective: Aminopeptidases
remove the amino acids from the N-terminal of proteins and peptides.
Aminopeptidase N (CD13) and leucine aminopeptidase
are involved in processing
and presentation of
pathogens to
immune cells. Also, enzyme activity in some viral infection and
tumors are high. In this study, the activity of CD13 in
serum with high
level of brucella antibody was measured. Due to the effect of protein,
cortisol,
bilirubin, and
total antioxidant
concentration on enzyme activity, these factors were also measured. Materials and Methods: In this study, 37 sera
with high level
of brucella antibody and 30 sera from healthy subjects were collected and
enzyme activity
was measured by
spectrophotometry
using L-leucine
para-nitro-anilid
substrate. Protein
concentration
was determined by
the Bradford method, total antioxidant levels was assessed by
spectrophotometry
method,
cortisol level was measured by ELISA method and total bilirubin
was determined by calorimetric
method. Results: CD13 activity
was not
significantly
higher in test
group than in
healthy subjects
and there was no
correlation between
enzyme activity
and
antibody titer
in test group. But
there was a
direct positive
and significant correlation between enzyme activity and cortisol
levels. Also, there was a
negative correlation between serum protein level with cortisol, bilirubin, and
total antioxidant. Also, there was a positive correlation between bilirubin and
total antioxidant in test group. Conclusion: There were no
correlation between brucella antibody titer and CD13
activity. Also, factors
such as
protein,
reducing
substances,
bilirubin
and
cortisol
did not
interfere with
the
results achieved. Background and Objective: Aminopeptidases
remove the amino acids from the N-terminal of proteins and peptides.
Aminopeptidase N (CD13) and leucine aminopeptidase
are involved in processing
and presentation of
pathogens to
immune cells. Also, enzyme activity in some viral infection and
tumors are high. In this study, the activity of CD13 in
serum with high
level of brucella antibody was measured. Due to the effect of protein,
cortisol,
bilirubin, and
total antioxidant
concentration on enzyme activity, these factors were also measured. Materials and Methods: In this study, 37 sera
with high level
of brucella antibody and 30 sera from healthy subjects were collected and
enzyme activity
was measured by
spectrophotometry
using L-leucine
para-nitro-anilid
substrate. Protein
concentration
was determined by
the Bradford method, total antioxidant levels was assessed by
spectrophotometry
method,
cortisol level was measured by ELISA method and total bilirubin
was determined by calorimetric
method. Results: CD13 activity
was not
significantly
higher in test
group than in
healthy subjects
and there was no
correlation between
enzyme activity
and
antibody titer
in test group. But
there was a
direct positive
and significant correlation between enzyme activity and cortisol
levels. Also, there was a
negative correlation between serum protein level with cortisol, bilirubin, and
total antioxidant. Also, there was a positive correlation between bilirubin and
total antioxidant in test group. Conclusion: There were no
correlation between brucella antibody titer and CD13
activity. Also, factors
such as
protein,
reducing
substances,
bilirubin
and
cortisol
did not
interfere with
the
results achieved. https://daneshvarmed.shahed.ac.ir/article_1575_70efba66d3d8d53194fb1a8446ae07fa.pdfShahed UniversityDaneshvar Medicine2716-972321220130622Evaluation of behavioral and movement disturbance in snoring children in 2011Evaluation of behavioral and movement disturbance in snoring children in 201165721576FAAbolfazlMozafariMohammad VakilAliabadiSiamakMohebiJournal Article20200926 Background and
Objective:
Snoring is one of the most significant causes of sleep disturbance in children.
Sleep behavior and movement disturbance (SBMD) is common and important and has
prominent effect in quality of daily life in this age group. This study aimed
to assess SBMD in children with a history of snoring in Qom. Materials and
Methods:
In this cross-sectional study, we have chosen 100 children (2-12 years old)
with a history of snoring for 3 months. Their parents fill out two
questionnaire of Berlin and Childhood Sleep Questionnaire. Data was collected
by organized interview and then data analysis was done using SPSS. A p value
less than 0.05 was significant. Results: The mean SBMD was
13.78±3. There were also 52% and 30% frequent and severe snoring, respectively,
apnea was observed in 18% of cases and snoring with troubling others was noted
in 27% of cases. In addition, bruxism was in 37% of cases, sleep walking was in
4% of cases and sleep talking was reported in 30% of cases. Conclusion: This study showed
the high prevalence of SBMD in children. It is important to educate subject
with sleep disturbance and to train their parents for helping to achieve better
sleep and early diagnosis of sleep problem in children. Background and
Objective:
Snoring is one of the most significant causes of sleep disturbance in children.
Sleep behavior and movement disturbance (SBMD) is common and important and has
prominent effect in quality of daily life in this age group. This study aimed
to assess SBMD in children with a history of snoring in Qom. Materials and
Methods:
In this cross-sectional study, we have chosen 100 children (2-12 years old)
with a history of snoring for 3 months. Their parents fill out two
questionnaire of Berlin and Childhood Sleep Questionnaire. Data was collected
by organized interview and then data analysis was done using SPSS. A p value
less than 0.05 was significant. Results: The mean SBMD was
13.78±3. There were also 52% and 30% frequent and severe snoring, respectively,
apnea was observed in 18% of cases and snoring with troubling others was noted
in 27% of cases. In addition, bruxism was in 37% of cases, sleep walking was in
4% of cases and sleep talking was reported in 30% of cases. Conclusion: This study showed
the high prevalence of SBMD in children. It is important to educate subject
with sleep disturbance and to train their parents for helping to achieve better
sleep and early diagnosis of sleep problem in children. https://daneshvarmed.shahed.ac.ir/article_1576_af5afd7f7c807171981d443ad4f4f648.pdfShahed UniversityDaneshvar Medicine2716-972321220130622Cognitive estimation in patients with schizophrenia, major depression disorder and normal individualsCognitive estimation in patients with schizophrenia, major depression disorder and normal individuals73821577FAJafarHasaniAliRastiJournal Article20200926 Background and Objective: Estimation abilities
are a group of processes that involve cognitive functions such as planning,
attention, abstract reasoning, and memory. The
goal of this study was to assess cognitive estimation in patients with
schizophrenia, major depression disorder (MDD) and normal individuals. Materials and
Methods:
Three groups including patients with schizophrenia, major depression disorder
(MDD) and normal individuals (n=22 for each group) were selected using
available sampling methods and inclusion and diagnostic criteria and were assessed by
Cognitive Estimation Test (CET). Results: Multivariate
analysis of variance (MANOVA) showed that patients with schizophrenia disorder
were impaired in all cognitive estimation dimensions in comparison with
patients with major depression disorder (MDD) and normal individuals and its total
score. Also, major depression patients performed worse than normal individuals
in size, weight and quantity of cognitive estimation dimensions and its total
score. Conclusion: A better understanding of the cognitive
estimation in schizophrenia and depression could help identify the risk and
modifying factors that influence the onset, severity and course of these
diseases. Background and Objective: Estimation abilities
are a group of processes that involve cognitive functions such as planning,
attention, abstract reasoning, and memory. The
goal of this study was to assess cognitive estimation in patients with
schizophrenia, major depression disorder (MDD) and normal individuals. Materials and
Methods:
Three groups including patients with schizophrenia, major depression disorder
(MDD) and normal individuals (n=22 for each group) were selected using
available sampling methods and inclusion and diagnostic criteria and were assessed by
Cognitive Estimation Test (CET). Results: Multivariate
analysis of variance (MANOVA) showed that patients with schizophrenia disorder
were impaired in all cognitive estimation dimensions in comparison with
patients with major depression disorder (MDD) and normal individuals and its total
score. Also, major depression patients performed worse than normal individuals
in size, weight and quantity of cognitive estimation dimensions and its total
score. Conclusion: A better understanding of the cognitive
estimation in schizophrenia and depression could help identify the risk and
modifying factors that influence the onset, severity and course of these
diseases. https://daneshvarmed.shahed.ac.ir/article_1577_7e1d842d0f7ee600116ffc6b2d87d83f.pdf