Volume 16, Issue 4 (12-2008)                   DMed 2008, 16(4): 11-18 | Back to browse issues page

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tehranian N, ghavi F, faghihzadeh S. A Controlled of Single Dose Oral Azithromycin versus Seven Day Doxycycline in the Treatment of Clamydia Cervicitis . DMed. 2008; 16 (4) :11-18
URL: http://daneshvarmed.shahed.ac.ir/article-1-88-en.html
, N_Tehranian@yahoo.com
Abstract:   (27459 Views)

 Introduction: Considering the high spread of Chlamydia cervicitis in Iran and its undesirable side-effects on women’s and their families’ health through causing infertility and transmitting it to the spouse and its bad economic impacts on the community, a remedy for this infection seems to be necessary. Considering the common remedial treatment (100mg of Doxycycline twice a day for 7 days).

 Aim: The main purpose of this study was comparison of the remedial effect of Doxycycline and Azitromcine on Chlamydia cervicitis in Nishabour.

 Materials & Methods: This survey is an experimental study of the type of one-sided blind accidental clinical test. All the 18-35 year-old women visiting the women clinic of the Kalin hospital in Nishabour, with the clinical symptoms of the Chlamydia cervicitis and been identified through medical examination and proved by laboratory kit to be infectious, have been divided into 2 groups of 116 subjects under study. The first group under remedy with edible Doxycyclin (100 mg twice a day for 7 days) and the second group were remedied by Azitromicine (1gr for one single day). More over, during the remedial period, both groups had to either refrain from sexual intercourse or use a barrier (like candom) and at 7, 14, 21- day intervals after the remedy onset time, the patients were observed

  Results: According to the results of this study:

  1- The rate of recovery from Chlamydia cervicitis in the cases of a single-day remedy with Azitromicine was the same as the 7-day cure with Doxycycline . Digest side-effects in these 2 groups were different, so that in the Azitromicine group no critical problem was observed while in Daxicycline group 1.7% of the subjects faced with high digest risk.

  2- In the cases of remedy with Azitromicine , due to its easy use and economically, as well as its higher effectiveness, the rate of patient reception has been higher in comparison to the cases of remedy with Doxycycline.

  3- In the Doxycycline group, besides the weekly-recovery of the symptoms, some patients even have not reached 100% recovery.

  Conclusion: The rate of recovery from Clamydia cervicitis in the cases of a single-day remedy with Azitromycin is the same as the 7-day cure with Doxycycline. But digest side-effects Azitromycin is least satisfaction patients is more and symptoms improved in first week therefore Azitromycin priority in recovery of Clamydia cervicitis.

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