تأثیر پیش آماده‌سازی با تمرین تناوبی شدید بر محافظت قلبی و عملکرد بطن چپ در برابر آسیب ایسکمی خون‌رسانی مجدد در موش‌های صحرایی نر

1. Powers SK, Smuder AJ, Kavazis AN, Quindry JC. Mechanisms of exercise-induced cardioprotection. Physiology 2014;29(1):27-38. 2. Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, et al. Heart disease and stroke statistics—2016 update: a report from the American Heart Association. Circulation 2016;133(4):e38-e360. 3. Powers SK, Lennon SL, Quindry J, Mehta JL. Exercise and cardioprotection. Current Opinion in Cardiology 2002;17(5):495-502. 4. Frasier CR, Moore RL, Brown DA. Exercise-induced cardiac preconditioning: how exercise protects your achy-breaky heart. Journal of Applied Physiology 2011;111(3):905-15. 5. French JP, Hamilton KL, Quindry JC, Lee Y, Upchurch PA, Powers SK.Exercise-induced protection against myocardial apoptosis and necrosis: MnSOD, calcium-handling proteins, and calpain. The Federation of American Societies for Experimental Biology Journal 2008;22(8):2862-71. 6. Quindry JC, Miller L, McGinnis G, Kliszczewicz B, Irwin JM, Landram M, et al. Ischemia reperfusion injury, KATP channels, and exercise- induced cardioprotection against apoptosis. Journal of Applied Physiology 2012;113(3):498-506. 7. Kavazis AN, McClung JM, Hood DA, Powers SK. Exercise induces a cardiac mitochondrial phenotype that resists apoptotic stimuli. American Journal of Physiology-Heart and Circulatory Physiology 2008;294(2):H928-35. 8. Lee Y, Min,K, Talbert EE, Kavazis AN, Smuder AJ, Willis WT, et al. Exercise protects cardiac mitochondria against ischemia-reperfusion injury. Medicine & Science in Sports & Exercise 2012;44(3):397-405. 9. Rahimi M, Shekarforoush S, Asgari AR, Khoshbaten A, Rajabi H, Bazgir B, et al. The effect of high intensity interval training on cardioprotection against ischemia-reperfusion injury in wistar rats. Experimental and Clinical Sciences 2015;14:237-246. 10. Powers SK, Quindry JC, Kavazis AN. Exercise-induced cardioprotection against myocardial ischemia–reperfusion injury. Free Radical Biology and Medicine 2008;44(2):193-201. 11. Frasier CR, Moore RL, Brown DA. Exercise-induced cardiac preconditioning: how exercise protects your achy-breaky heart. Journal of Applied Physiology 2011;111(3):905-15. 12. Quindry,J.C, Hamilton, K.L. Exercise and cardiac preconditioning against ischemia reperfusion injury. Current Cardiology Reviews 2013; 3(9), 220. 13. Dan Shan,Richard B. Marchase, and John C. Chatham. Overexpression of TRPC3 increases apoptosis but not necrosis in response to ischemia-reperfusion in adult mouse cardiomyocytes. American Journal of Physiology- Cell Physiology 2008; 294: C833–C841 14. Jian Xi, Seung-Kuy Cha, Chou-Long Huang. Cardioprotection by Klotho through downregulation of TRPC6 channels in the mouse heart. Nature Communications 2012; 4;3;1238. 15. Weissmann N, Sydykov A, Kalwa H, Storch U, Fuchs B, y Schnitzler MM, et al. Activation of TRPC6 channels is essential for lung ischaemia–reperfusion induced oedema in mice. Nature Communications 2012;3:649. 16. Shen B, Zhou S, He Y, Zhao H, Mei M, Wu X. Revealing the underlying mechanism of ischemia reperfusion injury using bioinformatics approach. Kidney and Blood Pressure Research 2013;38(1):99-108. 17. Zhao B, Yang H, Zhang R, Sun H, Liao C, Xu J, et al. The role of TRPC6 in oxidative stress-induced podocyte ischemic injury. Biochemical and Biophysical Research Communications 2015;461(2):413-20. 18. Avin KG, Coen PM, Huang W, Stolz DB, Sowa GA, Dubé JJ, et al. Skeletal muscle as a regulator of the longevity protein, Klotho. Frontiers in Physiology 2014;5:189. 19. Martín-Núñez E, Donate-Correa J, Muros-de-Fuentes M, Mora-Fernández C, Navarro-González JF. Implications of Klotho in vascular health and disease. World Journal of Cardiology 2014;6(12):1262. 20. Song S, Gao P, Xiao H, Xu Y, Si LY. Klotho suppresses cardiomyocyte apoptosis in mice with stress-induced cardiac injury via downregulation of endoplasmic reticulum stress. PLoS One 2013;8(12):e82968. 21. Matsubara T, Miyaki A, Akazawa N, Choi Y, Ra S-G, Tanahashi K, et al. Aerobic exercise training increases plasma Klotho levels and reduces arterial stiffness in postmenopausal women. American Journal of Physiology-Heart and Circulatory Physiology 2014;306(3):H348-H55. 22. Saghiv M, EG, MS, DB-S. Effects of Aerobic Exercise Training on S-Klotho in Young and Elderly. Jacobs Journal of Physiology 2015;1(1):001. 23. Michelsen MM, Stottrup NB, Schmidt MR, Lofgren B, Jensen RV, Tropak M, et al. Exercise-induced cardioprotection is mediated by a bloodborne, transferable factor. Basic Research in Cardiology 2012;107(3):260. 24.Guiraud T, Nigam A, Gremeaux V, Meyer P, Juneau,M, Bosquet L. High-intensity interval training in cardiac rehabilitation. Sports Medicine 2012;42:587-605. 25. Rankin A, Rankin A, MacIntyre P, Hillis W. Walk or run? Is high-intensity exercise more effective than moderate-intensity exercise at reducing cardiovascular risk? Scottish Medical Journal 2012;57(2):99-102. 26.Freyssin C, Verkindt C, Prieur F, Benaich P, Maunier S, Blanc P. Cardiac rehabilitation in chronic heart failure: effect of an 8-week, high-intensity interval training versus continuous training. Archives of Physical Medicine and Rehabilitation 2012;93:1359-64. 27.Gibala MJ, Little JP, MacDonald MJ, Hawley JA. Physiological adaptations to low‐volume, high‐inten- sity interval training in health and disease. Journal of Physiology 2012;590:1077-84. 28.Høydal MA, Wisløff U, Kemi OJ, Ellingsen Ø. Running speed and maximal oxygen uptake in rats and mice: practical implications for exercise training. European Journal of Cardiovascular Prevention and Rehabilitation 2007;14(6):753-60. 29. Kemi OJ, Haram PM, Loennechen JP, Osnes J-B, Skomedal T, Wisløff U, et al. Moderate vs. high exercise intensity: differential effects on aerobic fitness, cardiomyocyte contractility, and endothelial function. Cardiovascular Research 2005;67(1):161-72. 30. Azizi Y, Faghihi M, Imani A, Roghani M, Nazari A. Post-infarct treatment with [Pyr1]-apelin-13 reduces myocardial damage through reduction of oxidative injury and nitric oxide enhancement in the rat model of myocardial infarction. Peptides 2013;46:76-82. 31. Powers SK, Quindry JC, Kavazis AN. Exercise-induced cardioprotection against myocardial ischemia–reperfusion injury. Free Radical Biology and Medicine 2008;44(2):193-201. 32. Borges JP, Lessa MA. Mechanisms involved in exercise-induced cardioprotection: a systematic review. Arquivos Brasileiros de Cardiologia 2015;105(1):71-81. 33. French JP, Quindry JC, Falk DJ, Staib JL, Lee Y, Wang KK, et al. Ischemia-reperfusion-induced calpain activation and SERCA2a degradation are attenuated by exercise training and calpain inhibition. American Journal of Physiology-Heart and Circulatory Physiology 2006;290(1):H128-H36. 34. Ciampone S, Borges R, de Lima IP, Mesquita FF, Cambiucci EC, Gontijo JA. Long-term exercise attenuates blood pressure responsiveness and modulates kidney angiotensin II signalling and urinary sodium excretion in SHR. Journal of the Renin-Angiotensin-Aldosterone System 2011;12(4):394-403. 35. Kawamura T, Yoshida K, Sugawara A, Nagasaka M, Mori N, Takeuchi K, et al. Regulation of skeletal muscle peroxisome proliferator-activated receptor γ expression by exercise and angiotensin-converting enzyme inhibition in fructose-fed hypertensive rats. Hypertension Research 2004;27(1):61-70. 36.Lim K, Lu T-S, Molostvov G, Lee C, Lam F, Zehnder D, et al. Vascular Klotho deficiency potentiates the development of human artery calcification and mediates resistance to fibroblast growth factor 23clinical perspective. Circulation 2012;125(18):2243-55. 37. Mitobe M, Yoshida T, Sugiura H, Shirota S, Tsuchiya K, Nihei H. Oxidative stress decreases klotho expression in a mouse kidney cell line. Nephron Experimental Nephrology 2005;101(2):e67-e74. 38. Saito K, Ishizaka N, Mitani H, Ohno M, Nagai R. Iron chelation and a free radical scavenger suppress angiotensin II‐induced downregulation of klotho, an anti‐aging gene, in rat. FEBS letters 2003;551(1-3):58-62. 39. Zhang H, Li Y, Fan Y, Wu J, Zhao B, Guan Y, et al. Klotho is a target gene of PPAR-γ. Kidney International 2008;74(6):732-9.