تأثیر روش‌های تمرینی مختلف بر BDNF سرم، عملکرد جسمانی، ناتوانی عملکردی و کیفیت زندگی افراد مبتلا به مولتیپل اسکلروزیس

نویسندگان

1 گروه فیزیولوژی ورزشی. دانشگاه آزاد اسلامی واحد اسلامشهر. تهران. ایران

2 گروه فیزیولوژی ورزشی. دانشگاه آزاد واحد مشهد. مشهد. ایران

3 گروه فیزیولوژی ورزشی. دانشگاه آزاد تهران مرکز. تهران. ایران

چکیده

مقدمه و هدف: هدف از انجام تحقیق حاضر بررسی تأثیر روش‌های تمرینی مختلف بر BDNF سرم، عملکرد جسمانی، ناتوانی عملکردی و کیفیت زندگی افراد مبتلا به مولتیپل اسکلروزیسمی باشد.
 
مواد و روش‌ها: پژوهش حاضر از نوع نیمه تجربی و کاربردی است. به این منظور بیماران زن غیرفعال مبتلا به بیماری ام‌اس به‌وسیله آزمون EDSS توسط پزشک متخصص مغز و اعصاب بررسی و انتخاب شدند. سپس از بین آزمودنی‌های مورد نظر 52 بیمار انتخاب و به صورت تصادفی در چهار گروه ده نفره (کنترل، تمرینات پیلاتس، ایروبیک در آب و ماساژ) تقسیم‌بندی شدند. برای بررسی مداخلات تمرین، قبل و بعد از 12 هفته به صورت پیش‌آزمون و پس‌آزمون ارزیابی متغیرها انجام شد.
 
نتایج: نتایج نشان داد در تمامی متغیرها بین گروه‌های مختلف تفاوت معناداری مشاهده شد)005.0P<). همچنین آزمون تعقیبی بونفرونی نشان داد در متغیرهای BDNF، کیفیت زندگی، تعادل و ناتوانی اسوستری بین گروه‌های تمرینی و کنترل تفاوت معناداری مشاهده شد)005.0P<)؛ اما تفاوتی بین گروه پیلاتس و ماساژ مشاهده نشد )005.0P<). همچنین نتایج نشان از کاهش میزان درد در گروه ایروبیک در آب و تفاوت معنادار، بین گروه‌های ایروبیک در آب، پیلاتس و ماساژ با گروه کنترل بود)005.0P<)؛ اما تفاوتی بین سایر گروه‌ها مشاهده نشد )005.0P<). همچنین در متغیر میزان EDSS در گروه ایروبیک در آب از همه بیشتر بهبودیافته بود و موجب ایجاد تفاوت معناداری با گروه‌های کنترل، پیلاتس و ماساژ شده است)005.0P<).
 
نتیجه‏ گیری: به نظر می‌رسد ایروبیک در آب یک استراتژی تمرینی مناسب برای بهبود بیماران ام‌اس به نسبت سایر روش‌های تمرینی است.

کلیدواژه‌ها


عنوان مقاله [English]

The effect of different training methods on serum BDNF, physical performance, functional disability, and quality of life in patients with multiple sclerosis

چکیده [English]

Objective: The present research aimed to investigate the effect of different training methods on serum BDNF, physical performance, functional disability and quality of life in people with multiple sclerosis.
 
Materials and Methods: The present research type was semi-experimental and applied. For this purpose, inactive female patients with MS were examined and chosen by a neurologist through EDSS test. Then, 52 patients of the intended subjects were then selected and randomly divided into four groups of ten members (Control, Pilates training, water aerobics, and massage). The variables were evaluated as pre-test and post-test before and after 12 weeks to investigate training interventions.
 
Results: The results showed a significant difference in all variables between different groups (p < 0.005). Also, Bonferroni post hoc test showed a significant difference between training and control groups in the variables of BDNF, quality of life, Oswestry balance and disability (p< 0.005). But no difference was observed between Pilates and massage groups (p>0.005). In addition, the results indicated a reduction in the degree of pain in water aerobics group and a significant difference between water aerobics, Pilates and massage groups and the control group (p<0.005). But no difference was observed between other groups (p>0.005). Also, the variable of EDSS level was most improved in water aerobics group. This caused a significant difference between this group and the control, Pilates and massage groups (p<0.005).
 
Conclusion: It appeared water aerobics is a good training strategy to improve MS patients as compared to other training methods.

کلیدواژه‌ها [English]

  • Serum BDNF
  • Quality of Life
  • Multiple Sclerosis
  • Massage
  • Water aerobics
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