Volume 18, Issue 5 (12-2010)                   DMed 2010, 18(5): 41-50 | Back to browse issues page

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Ghanbari A, Farmanbar R, Mansour-Ghanaei F. The study of life quality in patients with Hepatitis C and its comparison with healthy people and presentation of a structural model . DMed. 2010; 18 (5) :41-50
URL: http://daneshvarmed.shahed.ac.ir/article-1-199-en.html
, at_ghanbari@gums.ac.ir
Abstract:   (8920 Views)

Background and objective: Hepatitis C is an asymptomatic disease. The quality of life is a major concern in these patients. In this research, we compared quality of life in hepatitis c with healthy people and finally presented a structural model about it.


Materials and Methods: This is an analytical study in which a total of 61 patients with confirmed hepatitis C and 78 healthy accompaniers of them were included. A questionnaire composed of Persian translation of SF-36 items and Sweden QOL was used for measuring the HRQOL. Then, data were analyzed using SPSS16 and LISREAL 8.80.


Results: Total adjusted score of HRQOL (mean ± SE) was 60.77 ± 3.95 and 67.13 ± 4.80 in patients versus control group (p<0.0001). Age and ALT were 0.15 and -0.19 and had a path coefficient respectively with physical health. Age and Co disease were 0.26 and -0.36 and had a path coefficient respectively with psychological health. Physical health as a mediator accounted for 95 % of the variance and psychological health as a mediator accounted for 78 % of the variance in quality of life.


Conclusion: This study showed that hepatitis C is responsible for great alterations in HRQOL. Every effort is to be made to provide structural models in prediction of quality of life that would play a significant role in resolving of problems.

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