Volume 23, Issue 124 (9-2016)                   daneshvarmed 2016, 23(124): 51-60 | Back to browse issues page


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The effect of high-intensity interval training on lung parenchymal and non-parenchymal structural changes . daneshvarmed. 2016; 23 (124) :51-60
URL: http://daneshvarmed.shahed.ac.ir/article-1-1515-en.html

Abstract:   (1063 Views)

Background and Objective: The available information in relation to the effect of high-intensity interval training on lung structural changes are limited. The aim of this study was to evaluate the effect of a high-intensity interval training on structural changes in lung parenchymal and non-parenchymal tissue in male Wistar rats.

Materials and Methods: Samples of this study were 12 male Wistar rats (4 weeks old, 68±9 g), healthy, and had no history of disease and divided into training and control groups (exercise training = 6, control = 6). High-intensity interval training was carried out for 9 weeks. The samples started training program with 25 m/min (first week) and with 70 m/min at the end (ninth week). Finally, lung tissue was extracted for stereological and histological tests.

Results: The findings showed that after 9 weeks of high-intensity interval training, parenchymal volume, number of alveoli and respiratory surface significantly decreased. Also, non-parenchymal and peribronchovascular volume significantly increased.

Conclusion: Based on research findings, it seems that 9 weeks of high-intensity interval training leads to lung inflammation and structural disorders. These effects are possibly associated with reduction of maximum gas exchange in lung blood-gas barrier during exercise performance and challenge of overall health in lung.

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Type of Study: Research | Subject: فیزیولوژی ورزش

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