Investigation of vacA status and cagA in patients with peptic ulcer disease
Zohreh
Khodaii
گروه ژنتیک، دانشکده پزشکی، دانشگاه علوم پزشکی و خدمات درمانی شهید بهشتی
author
Akram Sadat
Tabatabaei Panah
باشگاه پژوهشگران جوان، دانشگاه آزاد اسلامی، واحد تهران شرق
author
Sayyed Mohammad Hossein
Ghaderian
گروه ژنتیک، دانشکده پزشکی، دانشگاه علوم پزشکی و خدمات درمانی شهید بهشتی
author
Reza
Akbarzadeh Najar
گروه ژنتیک، دانشکده پزشکی، دانشگاه علوم پزشکی و خدمات درمانی شهید بهشتی
author
text
article
2013
per
Background and Objective: Helicobacter
pylori (H. pylori) infection is one of
the most common gastrointestinal infections worldwide. Infection with H. pylori strains may results in different pathological
manifestation and increased oxidative stress lead to a strong inflammatory
response in gastric mucosa. There is continuing interest in identifying H. pylori
virulence factors that might predict the risk for symptomatic clinical
outcomes. The prevalence of cagA and vacA genes, proteins and were
determined.
Materials and Methods: The presence of IgG antibody against CagA
and VacA proteins was determined by using Western blotting technique. The presence of cagA gene and vacA alleles was examined by PCR. H. pylori-positive patients including PUD and NUD were used for these experiments. Results: Biopsies
were considered as H. pylori-positive and negative when both the rapid
urease test and bacterial culture gave positive and negative results
respectively. H. pylori-positive, cagA-positive, and vacA alleles (s1 and m2)
were predominant in all clinical outcomes. There was no significant association
between prevalence of CagA and VacA status and clinical outcomes. Conclusion: Our results suggest
that cagA-positive strains were predominant in patients. However, we
found no association between cagA and vacA status
and clinical outcomes and this virulence
factor is not associated with the development of PUD. In addition,
serological tests such as the western blotting are helpful in detecting
subjects infected with H. pylori strains in PUD and NUD.
Daneshvar Medicine
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https://daneshvarmed.shahed.ac.ir/article_1560_7588d92aa2c8792e903b50c02528ccfd.pdf
Studying the connection between psychological disorders symptoms and sexual dysfunctions
Gholamhosein
Ghaedi
دانشکده پزشکی دانشگاه شاهد
author
Mahdieh
Sasaninezhad
روانشناسی بالینی، دانشکده روانشناسی و علوم تربیتی، دانشگاه علامه طباطبایی
author
Azad
Sabeti
مشاوره، دانشکده روانشناسی و علوم تربیتی، دانشگاه علامه طباطبایی
author
text
article
2013
per
Background and Objective: Studies show that there is a connection between
psychological disorders symptoms and sexual dysfunctions. The aim of this study
is to examine the connection between psychological disorders symptoms and
sexual dysfunction and also to determine the role of psychological disorders
symptom in the development of sexual dysfunctions. Materials and
Methods: 200 individuals (115 female and 75 male) who referred to
psychological clinics in Tehran and Karaj (in 1390-1391 on the Iranian
calendar) were included in this study with a convenient sampling method. All
individual were asked to complete FSFI (for female), IIEF (for male) and SCL-90
Scales. Correlation and hierarchical regression were used to analyze the data. Results: The findings revealed
that there is a significant correlation between psychological disorders
symptoms and sexual dysfunctions. Hierarchical regression showed that
psychological disorders symptoms (especially phobia, depression, OCD, somatic
problems and paranoia symptoms) can remarkably predict sexual dysfunctions. Conclusion: There is a meaningful relation between psychological
disorders symptoms and sexual dysfunctions. Symptoms of some of psychological
disorders can explain sexual dysfunctions. Findings of this study are consonant
with that of many other previous researches
Daneshvar Medicine
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https://daneshvarmed.shahed.ac.ir/article_1561_375ade19007ff67181b4ef45f73364e2.pdf
The Effect of Abutment Surface Roughness on the Retention of Implant-Supported Crowns Cemented with Provisional Luting Cement
Seyed Shojaeddin
Shaegh
گروه آموزشی پروتزهای دندانی، دانشکده دندانپزشکی دانشگاه شاهد
author
Alimohammad
Salari
گروه آموزشی پروتزهای دندانی، دانشکده دندانپزشکی دانشگاه شاهد
author
Mohsen
Ayoubi
دانشکده دندانپزشکی دانشگاه شاهد
author
text
article
2013
per
Background and Objective: Surface roughness can increase the retention of castings
by sandblast that are micro retentive. This study compared the retention of
implant-supported crowns when used with 3 different surface roughness abutments
and one temporary cement.
Materials and Methods: Thirty abutments (DIO
implant- Cemented abutment,SAC 4814N(II)) were divided in three groups, first
group was standard machine surface,
second group sandblasted with 25 micron aluminum
oxide particles and third group was sandblasted with 50 micron than ten regular
diameter implant analogs were embedded in resin acrylic block and provisional
cement kerr Temp bond NE was used for cementation.90 metal coping were
fabricated and after cementation the
aging processing was done than the
retentive strength was tested with universal testing machine at cross head
speed of 0.5 mm/min, results were analyzed using One way ANOVA and Tukey test. Results: Retentive strength of
temp bond kerr with 50 micro sanbblasted abutment was statistically different
than two other groups(P < 0.001) .and between all the group standard abutment
was weakest. Conclusion: Surface modification
of implant abutment by sandblast may be an effective method to increase
retention of crown when provisional luting cement is used.
Daneshvar Medicine
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https://daneshvarmed.shahed.ac.ir/article_1562_4c4560b1339eed7e9853dcc1a18a4220.pdf
Effects of hydro-alcoholic extract of Lavandula officinalis aerial parts on acquisition and expression of morphine tolerance and dependence in male mice
Batoul
Rahmati
مرکز تحقیقات نوروفیزیولوژی و گروه فیزیولوژی ، دانشکده پزشکی ،دانشگاه شاهد
author
Ahmad
Baik Khormaizi
کارشناسی ارشد گروه فیزیولوژی دانشکده پزشکی، دانشگاه شاهد
author
Mohsen
Khalili
مرکز تحقیقات نوروفیزیولوژی دانشگاه شاهد
author
Mehrdad
Roghani
مرکز تحقیقات نوروفیزیولوژی دانشگاه شاهد
author
Fariba
Ansari
گروه فیزیولوژی دانشکده پزشکی، دانشگاه شاهد
author
text
article
2013
per
Background and Objective: Tolerance and
dependence are two major problems of chronic opioids use. Repeated application
of Lavandula officinalis has been recommended for a long time in Iranian
traditional medicine for some of nervous disorders like epilepsy and dementia.
Since anti-convulsant drugs are beneficial in treatment of morphine dependence
and with regard to anti-convulsant effects of Lavandula officinalis, the
effects of Lavandula officinalis extract (LOE) was studied on
acquisition and expression of morphine tolerance and dependence and it was
compared with methadone.
Materials and
Methods: Morphine was injected either
acutely(100 mg/kg) or chronically, with gradually increasing doses twice daily
for 7 days, Exept in 8th day in which morphine was administrated in a single
dose (100 mg/kg). In either acutely or chronically with: saline, LOE 200 mg/kg,
LOE 400 mg/kg, methadone 5 mg/kg, methadone + LOE 200, methadone + LOE 400 was administrated 60 min prior
to morphine injection. Morphine tolerance was measured by tail immersion test,
before and after administration of morphine in test day. Morphine dependence
was also evaluated by counting the number of jumps after injection of naloxone
(5mg/kg) in test day. All drugs were given in a volume of 0.3 ml
intraperitoneally. Results: LOE
and methadone, significantly decreased acquisition (but not expression) of
morphine tolerance and dependence (P < 0.05). Chronic administration of LOE
and (not methadone) reduced physical dependence induced by single dose of
morphine (P < 0.05). Conclusion: Chronic
administration of Lavandula officinalis better than methadone inhibits
morphine tolerance and dependence in mice.
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https://daneshvarmed.shahed.ac.ir/article_1563_c5025380b48799ea81c0d426e66cfabc.pdf
Effectiveness of Education Program on Smoking Cessation Consistence Based on Trans theoretical Model (TTM)
Davood
Hekmatpoue
گروه پرستاری، دانشکده پرستایی و مامایی، دانشگاه علوم پزشکی اراک
author
Mohammad Ali
Ouroji
گروه بهداشت عمومی، دانشکده بهداشت، دانشگاه علوم پزشکی اراک
author
Mohsen
Shamsi
گروه بهداشت عمومی، دانشکده بهداشت، دانشگاه علوم پزشکی اراک
author
text
article
2013
per
Background
and Objective: Smoking
cessetation can prevent four million people death aroud the world but its
succeeding is low. The aim of this study was to determine to effectiveness of
educational program on smoking cessation consistence based on transtheoritical
model (TTM).
Materials and Methods: In the randomized
clinical trial study, 110 smoker who were allocation controll and treatment
group in Khomein in Arak city 2012. Data collection with standard measure based
on TTM construct and fagernstrom test (FNDT). Treatment group received five
sessions in person counceling, nicutin replacement thrapy (NRT)
with nocitine chewing gum, line follow up and self help mannual. After 3 and 6
month assess smoking cessation and finally data with statistical Chi-square,
T-test and T-paired test analyzed. Results: The
mean age of participant in treatment and controll group was 39.16± 9.12 and 38.12± 9.14 years respectively and don’t significant (P=0.32). Befor of intervention the mean of dependent
nicotin in control and tratment groups was 5.12±2.12 and 5.49±2.76 respectively based on FNDT and after of 6 month followup in
treatment group was decreased significantly (p=0.02). Conclusion: Performing
simioltaneosly intervention including in person counceling, NRT and line
followup are very beneficcial in people who are in preparation stage and should
be considered in cessetion programs.
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https://daneshvarmed.shahed.ac.ir/article_1564_542f97174a10c4c091d5b8197f84e82a.pdf
A comparison between behavior-nutritional, and
Mojgan
Agah Heris
گروه روانشناسی و مرکز تحقیقات علوم رفتاری دانشگاه علوم پزشکی شهید بهشتی و دانشگاه پیامنور سمنان
author
Masoud
Janbozorgi
گروه روانشناسی دانشکده علوم انسانی، پژوهشگاه حوزه و دانشگاه، قم
author
Avisa
Najimi
دانشگاه آزاد اسلامی واحد علوم و تحقیقات، اصفهان
author
Ahmad
Alipour
گروه روانشناسی دانشکده علوم انسانی، دانشگاه پیام نور تهران
author
AhmadAli
Noorbala
گروه روانپزشکی دانشکده پزشکی، دانشگاه تهران
author
Shahnaz
Noohi
دانشگاه آزاد اسلامی، تهران
author
Neda
Golchin
دانشگاه پیام نور، تهران
author
text
article
2013
per
Background and Objective: One of the consequences of
overweight and obesity is dyslipidemia. Hence, this research is conducted to
compare the effectiveness of behavior-nutritional and Beck cognitive therapy
combing to dietary-physical activity prescriptions on declining overweight, and
modifying lipid profile among overweight and obese females. Materials and Methods: Applying semi experimental design and using convenient sampling method, 32 volunteer females
with BMI≥25 eligible to exclude- include criteria were selected and randomly
assigned into two experimental groups (each groups includes 16 subjects). Prior
to, after, and 3 months later than each intervention, all participants' weight,
height, and lipid profile were measured. Results: Data analysis with 16th version of SPSS and
applying with repeated measures analysis of variances method revealed that both
interventions could significantly decrease the weight, TG and TC (P < 0.05), and HDL
were increased significantly (P < 0.05), too. But, there were no significant
differences between two interventions (0.05
Daneshvar Medicine
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https://daneshvarmed.shahed.ac.ir/article_1565_98057298544da5f3a2e7e313bd24ebcc.pdf
The relationship between the pro-inflammatory markers with lipid peroxidation after water-based regular exercise and ginger supplement in breast cancer
Zohre
Fathi Bayyatiani
دانشکده تربیت بدنی و علوم ورزشی، دانشگاه مازندران
author
Valiollah
Dabidi Roshan
گروه فیزیولوژی ورزش، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه مازندران
author
Asma
Ayaz
دانشکده علوم انسانی، دانشگاه آزاد ساری
author
Mehran
Hoseinzadeh
دانشگاه علوم پزشکی جندی شاپور اهواز
author
text
article
2013
per
Background and Objective: Recent studies have demonstrated the obese–induced oxidative stress
and inflammation are risk factors for breast cancer. The aim of this study was
to determine the relationship of the pro-inflammatory markers, lipid
peroxidation and body fat percentage after 6 weeks of regular water-based
exercise and ginger supplement in obese women
with breast cancer.
Materials and Methods: In a
semi-experimental study, forty obese women diagnosed with breast cancer with
weight 76±9 kg and fat mass of 41.8±4 percent were randomly divided into four
groups: placebo, water-based exercise, ginger supplement and a combined group
of water-based exercise and ginger supplement. Subjects of the ginger
supplement and combined group were receiving 4 capsules of ginger powder on a
daily basis (each capsule contained 750 mg), for 6 weeks. The water-based
exercise training program was collected at a progressive intensity and time: 4
times a week for 6 weeks. Results: Implementation
of water-based exercise, ginger supplement and the combined programs caused a
significant decrease in concentration of interleukin -6
(IL-6) and C-reactive protein (CRP), malondialdehyde (MDA) and fat mass.
However, considering Pearson correlation coefficient, it was concluded that
just the relationship between fat mass and MDA in the ginger supplement group
was significant (r= 0.63, p= 0.05). Conclusion: Although performing water-based
exercise and ginger supplement programs attenuate systemic inflammation and
oxidative stress in obese women with breast cancer, there was no relationship between stress and changes of pro-inflammatory markers.
Daneshvar Medicine
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https://daneshvarmed.shahed.ac.ir/article_1566_dab6a2bf7792f046780c033b8c23a91e.pdf
The interaction effect between âSelf-Compassionâ and âRuminationâ of depressed patients in âCompassion Focused Therapyâ
Fatemeh
Noorbala
دانشکده روانشناسی و علومتربیتی، دانشگاه علامه طباطبایی
author
Ahmad
Borjali
گروه روانشناسی، دانشکده روانشناسی و علومتربیتی، دانشگاه علامه طباطبایی
author
Ahmad Ali
Noorbala
بخش روانتنی بیمارستان امام خمینی، دانشگاه علومپزشکی تهران
author
text
article
2013
per
Background and Objective: The history of psychology is full of concepts evolved to
upgrade and improve therapies and mental health. The Compassionate Focused Therapy
(CFT) model is rooted in the concept of self-compassion in modern psychology.
The purpose of this research is to study the effectiveness of CFT on
depression, anxiety, and rumination of depressed patients according to their
self-compassion trait. Materials and Methods: This
study is designed as experimental pretest-posttest with an equivalent control
group. Nineteen depressed patients with available sampling were selected from a
psychiatric clinic and randomly divided into two groups. The experiment group
participated in 12 sessions of Compassion Focused Group therapy (CFT). All
participants were assessed by Beck Depression Inventory-II (BDI-II), Anxiety
Scale (AS), Rumination Scale and Self-Compassion Scale (SCS) at the beginning,
final session and two month after the intervention (follow-up study). Data were
analysis by ANOVA and independent samples t-test with SPSS 18. Results: According to data
analysis, depression and anxiety of the experiment group significantly
decreased in the follow-up study (p < 0.05).
In addition, the interaction between intervention and self-compassion was
significant on the rumination. Conclusion:
This
study showed that CFT could be an effective therapy on depression and anxiety
of depressed patients. In addition, people who had higher levels of
self-compassion benefited more from our intervention and their rumination
decreased. On the other hand, people who had lower level of self-compassion
experienced increased rumination.
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https://daneshvarmed.shahed.ac.ir/article_1567_435e027d0ff773067bfd9645dafe2922.pdf
Evaluation of the effect of conventional varnish and nano-silver containing varnish on microleakage of amalgam restoration
Roza
Haghgoo
گروه دندانپزشکی کودکان، دانشکده دندانپزشکی دانشگاه شاهد
author
Mohammad
Ataie
مرکز پلیمر ایران
author
Mohammad Bagher
Rezvani
گروه دندانپزشکی ترمیمی، دانشکده دندانپزشکی دانشگاه شاهد
author
Akram
Labibzadeh
دندانپزشک
author
text
article
2013
per
Background
and Objective: Microleakage is one of the most important problems in
dentistry. Varnish is commonly used to reduce microleakage. Nanotechnology has
recently produced cosmetic dental materials with better mechanical properties.
The aim of this study was to compare the microleakage of dental restorations
using traditional varnish and varnish containing nano-silver. Materials
and Methods: In this research study, for preparing a nano-silver varnish,
nano- silver powders was added to soluble varnish with a certain weight
standard. Then, 30 teeth were divided into three groups for each time period (3
days and 1 month): nano silver-containing varnish, varnish, and without varnish
(control group). For each sample, two class 5 cavities were prepared (one side
of the buccal and lingual) with appropriate dimensions and optimum turbine and
in each cavity (except to control) suitable varnish was applied and the
cavities was filled with amalgam. Then, the teeth immersed in water for 3 days
and 1 month depending on related groups. After the appropriate time has
elapsed, the teeth were thermo-cycled. The teeth were placed in 2% Fushin. The
teeth were divided into two halves from the middle of class 5 cavity. The
sections were evaluated by stereomicroscope and dye penetration was measured.
The data were analyzed by Two-Way ANOVA and Tukey multiple comparison test. Results:
Tukey multiple comparison analysis showed that there was a significant
difference between nano-silver containing varnish group and two other groups.
Conclusion: Based on the results of this study, applying of
nano-silver to varnish reduces microleakage in amalgam restoration.
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https://daneshvarmed.shahed.ac.ir/article_1568_311bb5a3c54200091c79b9342bfbe4e0.pdf